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Invitrogen
UCHL3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-33098
Product Specifications
Species Reactivity
Dog,
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from internal region of human UCHL3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Dog, Elephant, Opossum, Turkey, Chicken, Lizard (100%); Orangutan, Monkey, Bovine, Horse, Rabbit, Pig, Salmon (94%); Pufferfish, Zebrafish, Stickleback, Water flea (89%); Xenopus (83%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: testicular tissue protein Li 221; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase; ubiquitin carboxyl-terminal hydrolase-6; ubiquitin thioesterase L3; ubiquitin thiolesterase; UCHL3; unnamed protein product
Gene Aliases: RGD1561196; UCH-6; UCH-L3
UniProt ID: (Human) P15374, (Mouse) Q9JKB1, (Rat) Q91Y78
Entrez Gene ID: (Chicken) 395626, (Human) 7347, (Dog) 476947, (Mouse) 50933, (Rat) 498560
ubiquitin-dependent protein catabolic process
protein ubiquitination
protein deubiquitination
protein catabolic process
post-translational protein modification
positive regulation of double-strand break repair via homologous recombination
reciprocal meiotic recombination
adult walking behavior
cellular response to insulin stimulus
meiotic DNA double-strand break formation
eating behavior
positive regulation of fat cell differentiation
retina development in camera-type eye
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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