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Invitrogen
UCMA Polyclonal Antibody
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产品信息
PA5-20768
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 16 amino acid peptide near the carboxy terminus of human UCMA.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is SW1353 cell lysate.
PA5-20768 can be used with blocking peptide PEP-0882.
靶标信息
UCMA is a gene that encodes for a protein that is specific to chondrocytes and highly charged. This protein is expressed abundantly in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the protein has been associated with osteoarthritis in humans. Alternative splicing of the gene results in multiple transcript variants that encode different isoforms. UCMA is also associated with diseases such as Osteoarthritis and Poland Syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Gla-rich protein; Unique cartilage matrix-associated protein; Upper zone of growth plate and cartilage matrix associated protein
基因别名: 1110017I16Rik; AW121955; C10orf49; GRP; GRP/UCMA; UCMA
UniProt ID: (Human) Q8WVF2, (Mouse) Q14BU0
Entrez Gene ID: (Human) 221044, (Mouse) 68527
