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Invitrogen
USP12 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-104193
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human USP12(Accession O75317), corresponding to amino acid residues N134-T184.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total USP12.
靶标信息
Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme 12; member of the deubiquitinating enzyme (DUB) family; Ubiquitin carboxyl-terminal hydrolase 12; ubiquitin hydrolyzing enzyme 1; Ubiquitin specific peptidase 12; ubiquitin specific protease 12; ubiquitin specific protease 12 like 1; Ubiquitin thioesterase 12; ubiquitin thiolesterase 12; Ubiquitin-hydrolyzing enzyme 1; Ubiquitin-specific-processing protease 12; unnamed protein product
基因别名: UBH1; USP12; USP12L1
UniProt ID: (Human) O75317, (Rat) D0RB01, (Mouse) Q9D9M2
Entrez Gene ID: (Human) 219333, (Rat) 360763, (Mouse) 22217
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
metal ion binding
ubiquitinyl hydrolase activity
molecular_function
thiol-dependent ubiquitinyl hydrolase activity
cysteine protease
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