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Invitrogen
Ubinuclein 1 Polyclonal Antibody
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产品信息
PA5-111516
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AKKKVMAPSK IKVKESSTKP DKKVSVPSGQ IGGPIALPSD HQTGGLSIGA SSRELPSQAS GGLANPPPVN LEDSLDEDLI RNPASSVEA
Highest antigen sequence indentity to the following orthologs: Mouse - 73%, Rat - 75%.
靶标信息
Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HIRA-binding protein; Protein VT4; Ubinuclein-1; Ubiquitously expressed nuclear protein
基因别名: UBN1; VT; VT4
UniProt ID: (Human) Q9NPG3
Entrez Gene ID: (Human) 29855
