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Invitrogen
VIP Polyclonal Antibody
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VIP Antibody (PA5-94931) in IHC (P)
Immunohistochemistry (Paraffin) analysis of VIP in paraffin-embedded section of rat colon tissue using VIP Polyclonal Antibody (Product # PA5-94931). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 5 µg/mL dilution overnight at 4°C. Cy3 c... View More
产品信息
PA5-94931
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence in the middle region of human VIP (81-107aa HADGVFTSDFSKLLGQLSAKKYLESLM).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - IHC: human pancreatic cancer tissue, rat pancreas tissue, rat intestine tissue, mouse pancreas tissue, mouse intestine tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
VIP encodes a protein that belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC13587; PACAP-R-2; PHI, peptide histidine isoleucine; prepro-VIP; vasoactive intestinal polypeptide; VIP peptides; VIP-R-1
基因别名: PHM27; VIP; vip/phi27
UniProt ID: (Human) P01282, (Rat) P01283, (Mouse) P32648
Entrez Gene ID: (Human) 7432, (Rat) 117064, (Mouse) 22353
positive regulation of endothelial cell proliferation
G-protein coupled receptor signaling pathway
body fluid secretion
learning or memory
positive regulation of cell proliferation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
regulation of protein localization
negative regulation of apoptotic process
negative regulation of potassium ion transport
positive regulation of protein catabolic process
positive regulation of vasodilation
mRNA stabilization
negative regulation of smooth muscle cell proliferation
regulation of sensory perception of pain
positive regulation of penile erection
prolactin secretion
regulation of signal transduction
