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产品信息
PA5-58860
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2649553
产品详细信息
Immunogen sequence: TGADYIVKIF DRHGQKRSEI NLPGNCVAMD WDKDGDVLAV IAEKSSCIYL WDANTNKTSQ LDNGMRDQMS FLLWSKVGSF LAVGTVKG
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.
靶标信息
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Intraflagellar transport 144 homolog; WD repeat membrane protein PWDMP; WD repeat-containing protein 19
基因别名: ATD5; CED4; DYF-2; IFT144; KIAA1638; NPHP13; ORF26; Oseg6; PWDMP; SRTD5; WDR19
UniProt ID: (Human) Q8NEZ3
Entrez Gene ID: (Human) 57728
in utero embryonic development
gonad development
embryonic limb morphogenesis
embryonic camera-type eye development
intraciliary retrograde transport
cilium assembly
ear morphogenesis
embryonic cranial skeleton morphogenesis
neurological system process
digestive system development
ciliary receptor clustering involved in smoothened signaling pathway
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
myotome development
