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Invitrogen
WIPF1 Polyclonal Antibody
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WIPF1 Antibody (PA5-120518) in IHC (P)
Immunohistochemistry analysis of WIPF1 in paraffin-embedded human esophageal. Samples were incubated with WIPF1 Polyclonal antibody (Product # PA5-120518) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-120518
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human WIPF1 (NP_001070737.1).
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: RAW264.7, Mouse spleen.
Immunogen sequence: QLPSRSGVDS PRSGPRPPLP PDRPSAGAPP PPPPSTSIRN GFQDSPCEDE WESRFYFHPI SDLPPPEPYV QTTKSYPSKL ARNESRSGSN RRERGAPPLP P
靶标信息
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC111041; Protein PRPL-2; testicular tissue protein Li 226; WAS/WASL interacting protein family, member 1; WAS/WASL-interacting protein family member 1; WASP interacting protein; WASP-interacting protein; Wiskott-Aldrich syndrome protein interacting protein; Wiskott-Aldrich syndrome protein-interacting protein
基因别名: AI115543; D2Ertd120e; PRPL-2; WAS2; WASPIP; WIP; WIPF1
UniProt ID: (Human) O43516, (Rat) Q6IN36, (Mouse) Q8K1I7
Entrez Gene ID: (Human) 7456, (Rat) 117538, (Mouse) 215280
actin cortical patch assembly
protein complex assembly
endocytosis
actin polymerization or depolymerization
regulation of cell shape
actin filament-based movement
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of actin nucleation
actin cortical patch localization
response to other organism
actin cytoskeleton organization
positive regulation of protein export from nucleus
