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Invitrogen
WSB1 Polyclonal Antibody
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产品信息
PA5-72859
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
WSB1 antibody for a 16 amino acid peptide near the amino terminus of human WSB1. The immunogen is within amino acids 70 - 120 of WSB1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SOCS box-containing WD protein SWiP-1; WD repeat and SOCS box-containing 1; WD repeat and SOCS box-containing protein 1; WSB-1
基因别名: SWIP1; WSB-1; WSB1
UniProt ID: (Human) Q9Y6I7
Entrez Gene ID: (Human) 26118
