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Invitrogen
XRCC2 Polyclonal Antibody
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XRCC2 Antibody (PA5-119832) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded mouse testis tissue using XRCC2 Polyclonal Antibody (Product # PA5-119832). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the XRCC2 antibody at a dilution of... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-119832
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within human XRCC2 aa 1-200.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: Mouse brain tissue lysates, human kidney tissue lysates, mouse testis tissue.
Subcellular Location: Nucleus, centrosome.
靶标信息
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp781P0919; DNA repair protein XRCC2; recA/RAD51 family protein; X-ray repair cross-complementing protein 2
基因别名: 4921524O04Rik; 8030409M04Rik; RAD51; RecA; XRCC2
UniProt ID: (Mouse) Q9CX47
Entrez Gene ID: (Mouse) 57434
mitotic cell cycle
double-strand break repair via homologous recombination
in utero embryonic development
somitogenesis
DNA repair
DNA recombination
cellular response to DNA damage stimulus
response to X-ray
response to gamma radiation
neurogenesis
multicellular organism growth
strand invasion
negative regulation of neuron apoptotic process
positive regulation of neurogenesis
centrosome organization
regulation of fibroblast apoptotic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
