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Invitrogen
YES1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-80243
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Yes1 (7-35aa KENKSPAIKYRPENTPEPVSTSVSHYGAE).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL once reconstituted
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human U20S whole cell, human CACO-2 whole cell, human A431 whole cell, human HepG2 whole cell, human MCF-7 whole cell, human PC-3 whole cell. IHC: human mammary cancer tissue.
Target Information
YES1 is a recombinant human protein kinase that is a member of the SRC family of non-receptor tyrosine kinases and is the cellular homolog of the Yamaguchi sarcoma virus oncogene. It is involved in the regulation of cell growth and survival, including roles in apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: c-Src; cellular yes-1 protein; EC 2.7.10.2; p60-Src; pp60c-src; proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; unnamed protein product; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; Yamaguchi sarcoma oncogene; YES1 proto-oncogene, Src family tyrosine kinase
Gene Aliases: c-yes; HsT441; P61-YES; Yes
UniProt ID: (Human) P07947
Entrez Gene ID: (Human) 7525
negative regulation of inflammatory response to antigenic stimulus
transmembrane receptor protein tyrosine kinase signaling pathway
cell differentiation
T cell costimulation
protein modification process
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of vascular permeability
ephrin receptor signaling pathway
leukocyte migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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