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Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH.
Predicted reactivity: Mouse (86%), Rat (83%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protrudin; RP11-459F3.2; Spastic paraplegia 33 protein; zinc finger FYVE domain containing 27; Zinc finger FYVE domain-containing protein 27; zinc finger, FYVE domain containing 27
基因别名: PROTRUDIN; SPG33; ZFYVE27
UniProt ID: (Human) Q5T4F4
Entrez Gene ID: (Human) 118813