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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QPEDTNGDSGG QCVGLADAGL DLKGTCISES EECDFSTVID TPAANYLSNG CDSYGMQDPG VSFVPKTLPS KEDSVTEEKE IEESKSECYS N
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 77%.
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor; MADH-interacting protein; novel serine protease; protein phosphatase 1, regulatory subunit 173; smad anchor for receptor activation; zinc finger, FYVE domain containing 9
基因别名: MADHIP; NSP; PPP1R173; SARA; SMADIP
UniProt ID: (Human) O95405
Entrez Gene ID: (Human) 9372