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Invitrogen
ZNF366 Polyclonal Antibody
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产品信息
PA5-41676
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human ZNF366
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: LGAEGGQERD CAGRDECLSL RAFQSTRRGP SFSDYLYFKH RDESLKELLE
Sequence homology: Guinea Pig: 79%; Human: 100%; Pig: 86%; Rabbit: 79%
靶标信息
Zinc finger protein 366 (ZNF366), also known as Zinc finger estrogen receptor binding domain-containing protein 1, is a gene located on chromosome 5q31.2 that encodes a transcription factor characterized by zinc finger domains. These domains are crucial for DNA binding, allowing ZNF366 to regulate gene expression by interacting with specific DNA sequences. ZNF366 is involved in modulating the activity of various signaling pathways, including those related to hormone receptors, such as the estrogen receptor, impacting cellular processes like development, differentiation, and proliferation. The protein's specific functional roles are still under investigation, but it is thought to contribute to transcriptional regulation and chromatin remodeling. Altered expression or mutations of ZNF366 have been associated with certain cancers, particularly breast cancer, where its regulatory functions may influence tumorigenesis. Research on ZNF366 continues to explore its potential role in disease mechanisms and therapeutic strategies, particularly in oncology and endocrine-related disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DC-SCRIPT; Dendritic cell-specific transcript protein; Zinc finger protein 366
基因别名: DCSCRIPT; ZNF366
UniProt ID: (Human) Q8N895
Entrez Gene ID: (Human) 167465
