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Invitrogen
eIF3i Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-56301
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MGYQCFVSFF DLRDPSQIDN NEPYMKIPCN DSKITSAVWG PLGECIIAGH ESGELNQYSA KSGEVLVNVK EHSRQINDIQ LSRD
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 30%.
靶标信息
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: eIF-3-beta; eIF3 p36; eIF3i; Eukaryotic translation initiation factor 3 subunit 2; Eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TRIP-1
基因别名: 36kDa; D4Ertd632e; EIF3I; EIF3S2; TRIP1
UniProt ID: (Mouse) Q9QZD9, (Rat) B0BNA7
Entrez Gene ID: (Mouse) 54709, (Rat) 682390
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
