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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: FLDTLKVLVE HGADVNVPDG TGALPIHLAV QEGHTAVVSF LAAESDLHRR DAR
Highest antigen sequence indentity to the following orthologs: Rat - 45%, Mouse - 79%.
p19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CDK4I; Cyclin-dependent kinase 4 inhibitor D; MTS1; p16-INK4; p16-INK4a; p19-INK4d
基因别名: CDKN2D
Entrez Gene ID: (Human) 1032