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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total MYBL1 protein.
A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A-Myb; Myb-like protein 1; Myb-related protein A; MYBA; VMYB
基因别名: A-myb; AMYB; G1-419-6; MYBL1; repro9
UniProt ID: (Mouse) P51960
Entrez Gene ID: (Mouse) 17864