{"id":1178,"date":"2026-03-25T07:05:41","date_gmt":"2026-03-25T07:05:41","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/?p=1178"},"modified":"2026-04-22T21:59:27","modified_gmt":"2026-04-22T21:59:27","slug":"fmo-controls","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/fmo-controls\/","title":{"rendered":"\u8367\u5149\u51cf\u4e00\u5bf9\u7167(FMO controls)"},"content":{"rendered":"\n

Q Dr.\u8d5b\uff0c\u6211\u60f3\u77e5\u9053\u5728\u6d41\u5f0f\u5b9e\u9a8c\u4e2d\u9700\u8981\u8bbe\u7f6e\u54ea\u4e9b\u5bf9\u7167\u7ec4\u5462\uff1f<\/strong><\/p>\n\n\n\n

A <\/strong>\u9664\u4e86\u5e38\u89c4\u7684\u7a7a\u767d\u5bf9\u7167\u3001\u9634\u6027\u5bf9\u7167\u548c\u9633\u6027\u5bf9\u7167\u5916\uff0c\u6211\u4eec\u901a\u5e38\u8fd8\u4f1a\u8bbe\u7f6e\u5355\u67d3\u5bf9\u7167\u3001\u540c\u578b\u5bf9\u7167\u4ee5\u53caFMO\u5bf9\u7167\u3002<\/p>\n\n\n\n

Q \u90a3\u2026\u2026\u4ec0\u4e48\u662fFMO\u5bf9\u7167\u5462\uff1f<\/strong><\/p>\n\n\n\n

A <\/strong>FMO\u7684\u5168\u79f0\u662fFluorescence minus one\uff0c\u610f\u601d\u662f\u6d41\u5f0fPanel\u4e2d\u7684\u6240\u6709\u8367\u5149\u6297\u4f53\u51cf\u53bb\u5355\u4e2a\u8367\u5149\u6297\u4f53\u540e\u67d3\u8272\u7ec6\u80de\u6837\u672c\u3002<\/p>\n\n\n\n

Q \u6240\u6709\u7684\u6297\u539f\u90fd\u9700\u8981\u8bbe\u7f6eFMO\u5bf9\u7167\u5417\uff1f<\/strong><\/p>\n\n\n\n

A <\/strong>\u901a\u5e38\u5bf9\u4e8e\u8868\u8fbe\u4e30\u5ea6\u4f4e\u6216\u8fde\u7eed\u8868\u8fbe\u7684\u6297\u539f\uff0c\u624d\u6709\u5fc5\u8981\u8bbe\u7f6eFMO\u3002<\/p>\n\n\n\n

\u5728\u4f7f\u7528\u5355\u67d3\u5bf9\u7167\u8c03\u8282\u597d\u5408\u9002\u7684\u8865\u507f\u540e\uff0c\u6211\u4eec\u8981\u5bf9\u6d41\u5f0f\u6570\u636e\u8fdb\u884c\u5708\u95e8\u5206\u6790\uff0c\u8fd8\u4f9d\u8d56\u8367\u5149\u51cf\u4e00\u5bf9\u7167\uff08Fluorescence minus one\uff0cFMO\uff09<\/strong>\u8fd9\u79cd\u5bf9\u7167\u7ec4\u3002\u8fd9\u8282\u8bfe\u8ddf\u968f\u7740Dr.\u8d5b\u4e00\u8d77\u6765\u63a2\u7a76FMO\u5bf9\u6d41\u5f0f\u5b9e\u9a8c\u6570\u636e\u5206\u6790\u7684\u5e2e\u52a9\u6709\u591a\u5927\u3002<\/p>\n\n\n\n

\u4ec0\u4e48\u662fFMO\uff1f<\/strong><\/h2>\n\n\n\n

\u5728\u6d41\u5f0f\u5206\u6790\u5b9e\u9a8c\u4e2d\uff0c\u5bf9\u7167\u7ec4<\/strong>\u7684\u8bbe\u7f6e\u975e\u5e38\u91cd\u8981\u3002\u5408\u9002\u7684\u5bf9\u7167\u7ec4\uff0c\u80fd\u591f\u66f4\u51c6\u786e\u5730\u5e2e\u52a9\u6211\u4eec\u5bf9\u5b9e\u9a8c\u6570\u636e\u8fdb\u884c\u5708\u95e8\u3002\u63d0\u5230\u5bf9\u7167\uff0c\u6211\u4eec\u9996\u5148\u4f1a\u60f3\u5230\u7a7a\u767d\u5bf9\u7167\u3001\u9634\u6027\u5bf9\u7167\u3001\u9633\u6027\u5bf9\u7167\u3001\u5355\u67d3\u5bf9\u7167\u53ca\u540c\u578b\u5bf9\u7167<\/strong>\uff0c\u4f46\u662f\u5f88\u591a\u4eba\u4f1a\u5ffd\u7565\u6389FMO\u3002\u90a3\u4e48\u4ec0\u4e48\u662fFMO<\/strong>\u5462\uff1fFMO\u901a\u5e38\u662f\u6307\uff0c\u4f7f\u7528\u6263\u9664\u4e86\u4e00\u4e2a\u989c\u8272\u7684\u6240\u6709\u67d3\u8272\u7ec4\u5408\u6765\u6807\u8bb0\u6837\u54c1\u7684\u5bf9\u7167\u3002<\/strong>\u5728\u6263\u9664\u4e00\u4e2a\u989c\u8272\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u76f4\u89c2\u770b\u5230\u5176\u4ed6\u8367\u5149\u57fa\u56e2\u5728\u6263\u9664\u989c\u8272\u7684\u901a\u9053\u4e0a\u7684\u6ea2\u6f0f\uff0c\u4ece\u800c\u80fd\u66f4\u51c6\u786e\u5730\u8bbe\u7f6e\u5708\u95e8\u4f4d\u7f6e\u3002<\/p>\n\n\n\n

\u4e3a\u4e86\u66f4\u597d\u5730\u7406\u89e3FMO\u7684\u610f\u4e49\uff0c\u6211\u4eec\u4e00\u8d77\u6765\u770b\u56fe1\u7684\u793a\u4f8b\u3002\u5728\u56fe1\u7684\u5b9e\u9a8c\u4e2d\uff0c\u6211\u4eec\u53d6\u4e86\u5c0f\u9f20\u813e\u810f\uff0c\u5bf9\u5176\u4e2d\u7684\u8c03\u8282\u6027T\uff08Treg\uff09\u7ec6\u80de\u8fdb\u884c\u6d41\u5f0f\u5206\u6790\u3002\u82e5\u6211\u4eec\u4ee5\u7a7a\u767d\u7ec4\uff08\u56fe1.a\uff09\u6765\u5708\u5b9aFOXP3\u7684\u9633\u6027\u7ec6\u80de\u7fa4\uff0c\u4f1a\u5bfc\u81f4\u5b9e\u9a8c\u7ec4\uff08\u56fe1.c\uff09\u4e2dFOXP3\u9633\u6027\u7ec6\u80de\u7fa4\u7684\u6bd4\u4f8b\u504f\u9ad8\uff0c\u56e0\u6b64\u4ee5FOXP3-FMO\uff08\u56fe1.b\uff09\u6765\u5708\u95e8\u66f4\u4e3a\u5408\u9002\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u56fe1*. Treg\u7ec6\u80de\u67d3\u8272\u3002\u7528CD4-FITC\u3001CD25-APC\u3001FOXP3-PE\u67d3\u8272Treg\u7ec6\u80de\uff0c\u7528\u7a7a\u767d\u7ba1\u5708\u95e8\u4f1a\u5bfc\u81f4FOXP3\u9633\u6027\u7ec6\u80de\u7fa4\u504f\u591a\uff0c\u7528FOXP3-FMO\u7684\u4fe1\u53f7\u5708\u95e8\u6570\u636e\u66f4\u52a0\u51c6\u786e\u3002<\/p>\n\n\n\n

\u4ec0\u4e48\u65f6\u5019\u505aFMO\u5462\uff1f<\/strong><\/h2>\n\n\n\n

\u6d41\u5f0f\u914d\u8272\u65f6\u9700\u8981\u6ce8\u610f\u8868\u8fbe\u4e30\u5ea6\u4f4e\u7684\u6297\u539f\u642d\u914d\u8367\u5149\u5f3a\u7684\u57fa\u56e2\u3002\u5bf9\u4e8e\u8868\u8fbe\u4e30\u5ea6\u4f4e\u6216\u8fde\u7eed\u8868\u8fbe\u7684\u6297\u539f\uff0c\u9664\u4e86\u9009\u62e9\u8367\u5149\u5f3a\u7684\u57fa\u56e2\u5916\uff0c\u8bbe\u7f6eFMO\u4e5f\u5f88\u6709\u5fc5\u8981\u3002<\/p>\n\n\n\n

\u4ee5Treg\u7ec6\u80de\u67d3\u8272\u4e3a\u4f8b\uff0c\u5982\u56fe2\uff0c\u9996\u5148\u4f1a\u7528\u5230\u7a7a\u767d\u5bf9\u7167<\/strong>\uff0c\u6765\u8c03\u8282\u7ec6\u80deFSC\u548cSSC\u7684\u7535\u538b\u3002\u968f\u540e\u4e3a\u4e86\u8c03\u8282\u5404\u4e2a\u8367\u5149\u901a\u9053\u7684\u7535\u538b\u53ca\u76f8\u4e92\u95f4\u7684\u8865\u507f\uff0c\u4f1a\u4f7f\u7528\u5404\u81ea\u7684\u5355\u67d3\u5bf9\u7167<\/strong>\u3002\u5f53\u6297\u539f\u7684\u8868\u8fbe\u4e30\u5ea6\u4f4e\u6216\u8fde\u7eed\u8868\u8fbe\u65f6\uff0c\u6211\u4eec\u4e5f\u4f1a\u8bbe\u7f6e\u540c\u578b\u5bf9\u7167<\/strong>\u6765\u6392\u9664\u6297\u4f53\u975e\u7279\u5f02\u6027\u7ed3\u5408\u9020\u6210\u7684\u5047\u9633\u6027\u4fe1\u53f7\u3002\u5728\u591a\u8272\u67d3\u8272\u4e2d\uff0c\u7531\u4e8e\u8367\u5149\u8f83\u591a\uff0c\u53ef\u80fd\u5b58\u5728\u67d0\u4e2a\u8367\u5149\u5bf9\u76ee\u7684\u8367\u5149\u901a\u9053\u7684\u6ea2\u6f0f\u3002\u56e0\u6b64\u5bf9\u4e8e\u4e00\u4e9b\u8868\u8fbe\u4e30\u5ea6\u4f4e\u6216\u8fde\u7eed\u8868\u8fbe\u7684\u6297\u539f\u8fdb\u884c\u591a\u8272\u5206\u6790\u65f6\uff0c\u53ef\u4ee5\u8bbe\u7f6eFMO<\/strong>\u6765\u6709\u6548\u6392\u9664\u7531\u4e8e\u79bb\u6563\u8bef\u5dee\u9020\u6210\u7684\u80cc\u666f<\/strong>\u5bf9\u7ed3\u679c\u7684\u5f71\u54cd\uff0c\u80fd\u5e2e\u52a9\u66f4\u597d\u5730\u5708\u95e8<\/strong>\uff0c\u51c6\u786e\u533a\u5206\u9633\u6027\u7ec6\u80de\u7fa4<\/strong>\u3002\u6b63\u5982\u56fe1\u4e2d\u8868\u8fbe\u4e30\u5ea6\u4f4e\u7684FOXP3\uff0c\u82e5\u662f\u4e0d\u8bbe\u7f6eFMO\uff0c\u5f88\u96be\u51c6\u786e\u533a\u5206\u9633\u6027\u7ec6\u80de\u7fa4\u7684\u4f4d\u7f6e\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u56fe2.Treg\u7ec6\u80de\u67d3\u8272\u7ec4\u522b\u8bbe\u7f6e\u3002\u7a7a\u767d\u5bf9\u7167\u8c03\u8282FSC\u53caSSC\uff0c\u5355\u67d3\u5bf9\u7167\u8c03\u8282\u8865\u507f\uff0c\u540c\u578b\u5bf9\u7167\u6392\u9664\u975e\u7279\u5f02\u6027\u67d3\u8272\uff0c\u7ed3\u5408FMO\u5bf9\u8868\u8fbe\u4e30\u5ea6\u4f4e\u7684FOXP3\u8fdb\u884c\u5708\u95e8\u3002<\/p>\n\n\n\n

\u5982\u4f55\u64cd\u4f5cFMO\uff1f<\/strong><\/h2>\n\n\n\n

\u524d\u9762\u63d0\u5230\uff0cFMO\u662f\u6307\u4f7f\u7528\u6263\u9664\u4e86\u4e00\u4e2a\u989c\u8272\u7684\u6240\u6709\u67d3\u8272\u7ec4\u5408\u6765\u6807\u8bb0\u6837\u54c1\u7684\u5bf9\u7167\u3002\u90a3\u4e48\u5728\u67d3\u8272\u8fc7\u7a0b\u4e2d\uff0c\u6839\u636e\u6297\u539f\u8868\u8fbe\u60c5\u51b5\uff0c\u6211\u4eec\u9700\u8981\u9488\u5bf9\u82e5\u5e72\u4e2a\u8868\u8fbe\u4e30\u5ea6\u4f4e\u6216\u8fde\u7eed\u8868\u8fbe\u7684\u6297\u539f\uff0c\u5206\u522b\u5355\u72ec\u8bbe\u7f6eFMO\u3002\u5728\u51cf\u53bb\u8be5\u9776\u6807\u6297\u4f53\u7684\u540c\u65f6\uff0c\u4f1a\u7528\u5176\u5bf9\u5e94\u540c\u578b\u5bf9\u7167\u7684\u6297\u4f53\u8865\u4e0a\u8be5\u901a\u9053\u3002<\/p>\n\n\n\n

\u6211\u4eec\u4e00\u8d77\u6765\u770b\u56fe3\u7684\u4f8b\u5b50\u3002\u53d6\u5c0f\u9f20\u813e\u810f\u5355\u7ec6\u80de\u60ac\u6db2\uff0c\u901a\u8fc7\u6d41\u5f0f\u591a\u8272\u67d3\u8272\uff0c\u6765\u68c0\u6d4b\u7ecf\u523a\u6fc0\u540eT\u7ec6\u80de\u4e2dIFN-\u03b3\uff0cTNF-\u03b1\u548cIL-17A\u7b49\u7ec6\u80de\u56e0\u5b50\u7684\u8868\u8fbe\u60c5\u51b5\u3002\u5bf9\u4e8e\u8868\u8fbe\u4e30\u5ea6\u9ad8\u7684CD3\uff0cCD4\u548cCD8\u7b49\u9776\u6807\uff0c\u53ef\u4ee5\u65e0\u9700FMO\u8f85\u52a9\u5708\u95e8\uff1b\u7531\u4e8eIFN-\u03b3\u548c IL-17A\u7684\u8868\u8fbe\u4e30\u5ea6\u4f4e\uff0cTNF-\u03b1\u8fde\u7eed\u8868\u8fbe\uff0c\u9700\u8981\u5206\u522b\u8bbe\u7f6e\u9488\u5bf9\u8fd9\u4e09\u4e2a\u9776\u6807\u7684FMO\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u56fe3*.T\u7ec6\u80de\u80de\u5185\u56e0\u5b50\u67d3\u8272\u3002\u6839\u636eCD3\u3001CD4\u3001CD8\u5708\u51faTh\u7ec6\u80de\u53caTc\u7ec6\u80de\uff0c \u901a\u8fc7IFN-\u03b3\uff0cTNF-\u03b1\u548cIL-17A\u7684FMO\uff0c\u5708\u5b9a\u9633\u6027\u7ec6\u80de\u7fa4\u3002<\/p>\n\n\n\n

Question & Answer<\/strong><\/h2>\n\n\n\n

Q \u6240\u6709\u6297\u539f\u90fd\u9700\u8981\u8bbe\u7f6eFMO\u5417\uff1f<\/strong><\/p>\n\n\n\n

A <\/strong>\u5bf9\u4e8e\u4f4e\u8868\u8fbe\u4e30\u5ea6\u6216\u8fde\u7eed\u8868\u8fbe\u7684\u6297\u539f\uff0c\u624d\u9700\u8981\u8bbe\u7f6eFMO\u3002<\/p>\n\n\n\n

Q FMO\u4e5f\u9700\u8981\u56fa\u5b9a\u7834\u819c\u5417\uff1f<\/strong><\/p>\n\n\n\n

A <\/strong>\u5982\u679c\u6837\u672c\u7ba1\u9700\u8981\u56fa\u5b9a\u7834\u819c\u7b49\u64cd\u4f5c\uff0cFMO\u4e2d\u5bf9\u5e94\u6297\u4f53\u4e5f\u9700\u8981\u505a\u4e00\u6837\u7684\u64cd\u4f5c\u3002<\/p>\n\n\n\n

\"contact<\/a><\/figure>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Q Dr.\u8d5b\uff0c\u6211\u60f3\u77e5\u9053\u5728\u6d41\u5f0f\u5b9e\u9a8c\u4e2d\u9700\u8981\u8bbe\u7f6e\u54ea\u4e9b\u5bf9\u7167\u7ec4\u5462\uff1f A 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