{"id":2082,"date":"2026-05-11T02:23:25","date_gmt":"2026-05-11T02:23:25","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/?p=2082"},"modified":"2026-05-11T03:43:52","modified_gmt":"2026-05-11T03:43:52","slug":"electrospray-101-what-to-know-about-lc-ms-sources-and-a-first-look-at-optispray","status":"publish","type":"post","link":"https:\/\/www.thermofisher.cn\/blog\/electrospray-101-what-to-know-about-lc-ms-sources-and-a-first-look-at-optispray\/","title":{"rendered":"\u7535\u55b7\u96fe\u5165\u95e8\u6307\u5357\uff1a\u5173\u4e8eLC-MS\u79bb\u5b50\u6e90\u4f60\u9700\u8981\u4e86\u89e3\u7684\u77e5\u8bc6\u2014\u2014\u4ee5\u53ca\u5bf9Optispray\u6280\u672f\u7684\u9996\u6b21\u4e86\u89e3"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/industrial\/chromatography\/download-solution.html?icid=cn-blog-cmd\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"176\" src=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/05\/779-\u00d7-134-CMD-1024x176.jpg\" alt=\"\" class=\"wp-image-2088\" srcset=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/05\/779-\u00d7-134-CMD-1024x176.jpg 1024w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/05\/779-\u00d7-134-CMD-300x52.jpg 300w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/05\/779-\u00d7-134-CMD-768x132.jpg 768w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/05\/779-\u00d7-134-CMD-1536x264.jpg 1536w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/05\/779-\u00d7-134-CMD-2048x352.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/admin.acceleratingscience.com\/analyteguru\/wp-content\/uploads\/sites\/25\/2026\/02\/Blog-Image-Electrospray-1200x800-1-1024x683.jpeg\" alt=\"Abstract molecular network graphic with connected nodes in blue and gray.\" class=\"wp-image-19841\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-1-\u5728\u8d28\u8c31\u5206\u6790\u4e2d-\u79bb\u5b50\u6e90-\u5230\u5e95\u662f\u4ec0\u4e48\"><strong>1. \u5728\u8d28\u8c31\u5206\u6790\u4e2d\uff0c\u201c\u79bb\u5b50\u6e90\u201d\u5230\u5e95\u662f\u4ec0\u4e48\uff1f<\/strong><\/h3>\n\n\n\n<p>\u65e0\u8bba\u4f60\u4f7f\u7528\u7684\u662f\u6db2\u76f8\u8272\u8c31-\u8d28\u8c31\uff08LC-MS\uff09\u3001\u6210\u50cf\u8d28\u8c31\uff08imaging-MS\uff09\u8fd8\u662f\u539f\u751f\u8d28\u8c31\uff08native-MS\uff09\uff0c\u79bb\u5b50\u6e90\u90fd\u662f\u5206\u5b50\u4ece\u8272\u8c31\u4eea\u3001\u6bdb\u7ec6\u7ba1\u6216\u6837\u54c1\u53f0\u79bb\u5f00\u5e76\u53d8\u6210\u5e26\u7535\u6c14\u76f8\u7c92\u5b50\u7684\u5730\u65b9\uff0c\u8fd9\u4e9b\u7c92\u5b50\u53ef\u4ee5\u88ab\u8d28\u8c31\u4eea\u68c0\u6d4b\u5230\u3002\u4f60\u9009\u62e9\u7684\u79bb\u5b50\u6e90\u51b3\u5b9a\u4e86\u4f60\u80fd\u68c0\u6d4b\u5230\u7684\u5316\u5408\u7269\u7c7b\u578b\u3001\u53ef\u4f7f\u7528\u7684\u6d41\u901f\u8303\u56f4\uff0c\u4ee5\u53ca\u5206\u6790\u8fc7\u7a0b\u7684\u7a33\u5b9a\u6027\u548c\u91cd\u590d\u6027\u3002<\/p>\n\n\n\n<p>\u79bb\u5b50\u6e90\u4e3b\u8981\u5206\u4e3a\u4e24\u5927\u7c7b\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u771f\u7a7a\u7535\u79bb\uff08Vacuum ionization\uff09\uff1a\u7535\u5b50\u7535\u79bb\uff08EI\uff09\u3001\u5feb\u539f\u5b50\u8f70\u51fb\uff08FAB\uff09\u4ee5\u53ca\u4f20\u7edf\u7684\u57fa\u8d28\u8f85\u52a9\u6fc0\u5149\u89e3\u5438\u7535\u79bb\uff08MALDI\uff09\u662f\u5728\u4eea\u5668\u771f\u7a7a\u8154\u4f53\u5185\u4ea7\u751f\u79bb\u5b50\u7684\u3002<\/li>\n\n\n\n<li>\u5927\u6c14\u538b\u7535\u79bb\uff08API,&nbsp;Atmospheric-pressure ionization\uff09\uff1a\u7535\u55b7\u96fe\u7535\u79bb\uff08ESI\uff09\u3001\u5927\u6c14\u538b\u5316\u5b66\u7535\u79bb\uff08APCI\uff09\u3001\u5927\u6c14\u538b\u5149\u7535\u79bb\uff08APPI\uff09\uff0c\u4ee5\u53ca\u73b0\u4eca\u7684\u5927\u6c14\u538b\u57fa\u8d28\u8f85\u52a9\u6fc0\u5149\u89e3\u5438\u7535\u79bb\uff08AP-MALDI\uff09\u662f\u5728\u5f00\u653e\u73af\u5883\u4e2d\u4ea7\u751f\u79bb\u5b50\uff0c\u7136\u540e\u901a\u8fc7\u63a5\u53e3\u5f15\u5bfc\u8fdb\u5165\u771f\u7a7a\u7cfb\u7edf\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u5728\u6b64\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u7535\u79bb\u65b9\u6cd5\u7684\u4fe1\u606f\uff1a<a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/industrial\/mass-spectrometry\/mass-spectrometry-learning-center\/mass-spectrometry-technology-overview\/ionization-source-technology-overview.html\" target=\"_blank\" rel=\"noreferrer noopener\"><u>Ionization Source Technology Overview | Thermo Fisher Scientific \u2013 US \u79bb\u5b50\u6e90\u6280\u672f\u6982\u8ff0 | \u8d5b\u9ed8\u98de\u4e16\u5c14\u79d1\u6280 \u2013 \u7f8e\u56fd\u7f51\u7ad9<\/u><\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-2-\u4e3a\u4ec0\u4e48\u7535\u55b7\u96fe\u6539\u53d8\u4e86\u6e38\u620f\u89c4\u5219\"><strong>2. \u4e3a\u4ec0\u4e48\u7535\u55b7\u96fe\u6539\u53d8\u4e86\u6e38\u620f\u89c4\u5219\uff1f<\/strong><\/h3>\n\n\n\n<p>\u57281988\u5e74\uff0c\u7ea6\u7ff0\u00b7B\u00b7\u82ac\u6069\uff08John B. Fenn\uff09\u8bc1\u660e\u4e86\u4e00\u79cd\u9ad8\u538b\u7535\u4ea7\u751f\u7684\u7ec6\u5fae\u55b7\u96fe\u53ef\u4ee5\u5c06\u5b8c\u6574\u86cb\u767d\u8d28\u5f15\u5165\u6c14\u76f8\uff08\u89c1\u56fe\uff09\u3002\u8fd9\u4e00\u7a81\u7834\u4e3a\u4ed6\u8d62\u5f97\u4e862002\u5e74\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u7684\u4e00\u90e8\u5206\u3002\u7531\u4e8e\u7535\u55b7\u96fe\u4ea7\u751f\u591a\u7535\u8377\u79bb\u5b50\uff0c\u4ece\u800c\u4f7f\u5927\u5206\u5b50\uff08\u5982\u86cb\u767d\u8d28\uff09\u80fd\u591f\u9002\u5e94\u73b0\u4ee3\u8d28\u8c31\u5206\u6790\u4eea\u7684m\/z\u68c0\u6d4b\u8303\u56f4\u5185\u3002\u8fd9\u4e00\u5173\u952e\u53d1\u73b0\u5f00\u542f\u4e86\u4ee5\u4e0b\u9886\u57df\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u81ea\u4e0b\u800c\u4e0a\uff08bottom-up\uff09\u548c\u81ea\u4e0a\u800c\u4e0b\uff08top-down\uff09\u7684\u86cb\u767d\u8d28\u7ec4\u5b66<\/li>\n\n\n\n<li>\u4ee3\u8c22\u7ec4\u5b66\u548c\u8102\u8d28\u7ec4\u5b66<\/li>\n\n\n\n<li>\u86cb\u767d\u8d28\u590d\u5408\u7269\u548c\u6297\u4f53\u7684\u539f\u751f\u8d28\u8c31\u5206\u6790\uff08native MS\uff09<\/li>\n\n\n\n<li>\u4e34\u5e8a\u548c\u73af\u5883\u5b9e\u9a8c\u5ba4\u4e2d\u7684\u9776\u5411\u5b9a\u91cf\u5206\u6790<\/li>\n<\/ul>\n\n\n\n<p>\u6b64\u5916\uff0cESI\u8fd8\u53ef\u901a\u8fc7\u7eb3\u6d41\u7535\u55b7\u96fe\uff08nanoESI\uff09\u3001\u6bdb\u7ec6\u7ba1\u7535\u55b7\u96fe\uff08capillaryESI\uff09\u4ee5\u53ca\u52a0\u70ed\u7535\u55b7\u96fe\uff08HESI\uff09\u7b49\u53d8\u4f53\u9002\u5e94\u51e0\u4e4e\u4efb\u4f55\u6d41\u901f\u8303\u56f4\u2014\u2014\u53ef\u8986\u76d6\u4ece\u7eb3\u5347\u7ea7\u5230\u6beb\u5347\u7ea7\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/admin.acceleratingscience.com\/analyteguru\/wp-content\/uploads\/sites\/25\/2026\/02\/Chart-1200x800-1-1024x683.jpeg\" alt=\"Basic principle of electrospray ionization\" class=\"wp-image-19838\" \/><\/figure>\n\n\n\n<p class=\"has-text-align-center has-small-font-size\"><strong>\u7535\u55b7\u96fe\u7535\u79bb\u7684\u57fa\u672c\u539f\u7406\u3002<\/strong>\u9ad8\u7535\u538b\u4f5c\u7528\u4e8e\u9488\u5934\u5f62\u6210\u7ec6\u5fae\u7684\u5e26\u7535\u6db2\u6ef4\u55b7\u96fe\uff0c\u901a\u8fc7\u6eb6\u5242\u84b8\u53d1\u6536\u7f29\uff0c\u91ca\u653e\u51fa\u7528\u4e8e\u8d28\u8c31\u5206\u6790\u7684\u6c14\u76f8\u79bb\u5b50\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-3-\u5728\u8d5b\u9ed8\u98de\u5e73\u53f0\u4e0a\u5e94\u7528esi\u79bb\u5b50\u6e90\"><strong>3. \u5728\u8d5b\u9ed8\u98de\u5e73\u53f0\u4e0a\u5e94\u7528ESI\u79bb\u5b50\u6e90<\/strong><\/h3>\n\n\n\n<p>\u5982\u679c\u4f60\u66fe\u5728\u8d5b\u9ed8\u98de\u8d28\u8c31\u89e3\u51b3\u65b9\u6848\u4e0a\u8fdb\u884c\u8fc7\u86cb\u767d\u8d28\u7ec4\u5b66\u5b9e\u9a8c\uff0c\u4f60\u5df2\u7ecf\u81f3\u5c11\u64cd\u4f5c\u8fc7\u4e24\u79cdESI\u6e90\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Thermo Scientific OptaMax NG \u79bb\u5b50\u6e90\u6216 Thermo Scientific OptaMax Plus \u79bb\u5b50\u6e90\u914d\u5408 Thermo Scientific\u52a0\u70ed\u7535\u55b7\u96fe\u7535\u79bb\uff08HESI-II\uff09\u63a2\u9488\u2014\u2014\u53ef\u8f7b\u677e\u5b89\u88c5\u5230\u8d28\u8c31\u4eea\u524d\u7aef\uff0c\u8fd9\u4e00\u7cfb\u5217\u575a\u56fa\u8010\u7528\u7684\u79bb\u5b50\u6e90\u4e0e\u9002\u914d\u6027\u5f3a\u7684 HESI-II \u63a2\u9488\u642d\u914d\uff0c\u652f\u6301 1\u20132,000 \u00b5L\/min \u7684\u5bbd\u6d41\u901f\u8303\u56f4\uff0c\u4e3a\u5404\u79cd\u5e94\u7528\u63d0\u4f9b\u7075\u6d3b\u6027\u3002\u5927\u591a\u6570\u86cb\u767d\u8d28\u7ec4\u5b66\u5b9e\u9a8c\u5ba4\u5c06\u5176\u7528\u4e8e\u6821\u51c6\u6216\u5feb\u901f QC \u8fdb\u6837\uff1a\u901a\u8fc7 HESI \u63a2\u9488\u76f4\u63a5\u6ce8\u5165 Pierce FlexMix \u6eb6\u6db2\uff0c\u4eea\u5668\u5373\u53ef\u5b9e\u73b0\u4e9a ppm \u7ea7\u8d28\u91cf\u7cbe\u5ea6\u7684\u6821\u51c6\u3002<\/li>\n\n\n\n<li>Thermo Scientific EASY-spray\u79bb\u5b50\u6e90\u6216 Thermo Scientific NanoSpray Flex \u79bb\u5b50\u6e90\u2014\u2014\u6821\u51c6\u5b8c\u6210\u540e\uff0c\u62c6\u4e0b OptaMax \u79bb\u5b50\u6e90\uff0c\u6362\u4e0a\u4f4e\u6d41\u91cf\u79bb\u5b50\u6e90\u3002Thermo Scientific&nbsp;EASY-Spray&nbsp;\u79bb\u5b50\u6e90\u5c06 LC \u8272\u8c31\u67f1\u3001\u6db2\u4f53\u8fde\u63a5\u548c\u55b7\u9488\u96c6\u6210\u4e8e\u5355\u4e00\u624b\u7d27\u5f0f\u8fde\u63a5\u4e2d\uff0c\u6d88\u9664\u4e86\u6b7b\u4f53\u79ef\u548c\u624b\u52a8 x \u8f74\u5bf9\u9f50\u9700\u6c42\u3002NanoSpray Flex \u79bb\u5b50\u6e90\u63d0\u4f9b\u55b7\u9488\u548c\u51e0\u4f55\u7ed3\u6784\u8c03\u8282\uff0c\u5728\u9700\u8981\u5b9a\u5236\u914d\u7f6e\u65f6\u4e3a\u65b9\u6cd5\u5f00\u53d1\u5e26\u6765\u7075\u6d3b\u6027\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u5728\u5e38\u89c4\u81ea\u4e0b\u800c\u4e0a\u7684\u86cb\u767d\u8d28\u7ec4\u5b66\u5206\u6790\u4e2d\uff0c\u4f60\u53ef\u4ee5\u5728 Thermo Scientific Vanquish Neo UHPLC \u4e0a\u5e73\u8861 EASY-Spray \u8272\u8c31\u67f1\uff0c\u7528\u88c5\u6709 HESI-II \u63a2\u9488\u7684 OptaMax NG \u79bb\u5b50\u6e90\u5bf9\u8d28\u8c31\u4eea\u8fdb\u884c\u6821\u51c6\uff0c\u7136\u540e\u5207\u6362\u5230\u88c5\u8f7d nanoLC \u8272\u8c31\u67f1\u7684 EASY-spray \u79bb\u5b50\u6e90\uff0c\u6700\u540e\u5728 Orbitrap Astral Zoom \u8d28\u8c31\u4eea\u4e0a\u91c7\u96c6 30 \u5206\u949f DIA \u68af\u5ea6\u2014\u2014\u5168\u7a0b\u65e0\u9700\u63a5\u89e6\u8d28\u8c31\u4eea\u672c\u4f53\uff0c\u4ec5\u9700\u66f4\u6362\u524d\u7aef\u79bb\u5b50\u6e90\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-4-\u53e6\u4e00\u79cd\u79bb\u5b50\u6e90-\u539f\u4f4d\u8d28\u8c31\u4e2d\u7684\u9759\u6001\u7eb3\u55b7\u96fe-static-nano-spray\">4. \u53e6\u4e00\u79cd\u79bb\u5b50\u6e90\uff1a\u539f\u4f4d\u8d28\u8c31\u4e2d\u7684\u9759\u6001\u7eb3\u55b7\u96fe\uff08Static Nano-Spray\uff09<\/h3>\n\n\n\n<p>\u7535\u55b7\u96fe\u4e0d\u4ec5\u9650\u4e8e\u80bd\u6bb5\u5206\u6790\u3002\u5728\u539f\u4f4d\u8d28\u8c31&nbsp;\u4e2d\uff0c\u76ee\u6807\u662f\u5bf9\u5b8c\u6574\u3001\u672a\u53d8\u6027\u7684\u5206\u5b50\u8fdb\u884c\u8d28\u91cf\u5206\u6790\u2014\u2014\u5982\u75c5\u6bd2\u8863\u58f3\u3001\u6838\u7cd6\u4f53\u4e9a\u57fa\uff0c\u751a\u81f3\u9ad8\u8fbe&nbsp;10 MDa \u57fa\u56e0\u6cbb\u7597\u590d\u5408\u7269\u2014\u2014\u65e0\u9700 LC\u4e2d\u6240\u9700\u7684\u76d0\u548c\u6709\u673a\u6eb6\u5242\u3002\u5728\u8fd9\u91cc\u4e3b\u529b\u5de5\u5177\u662f\u9759\u6001\u7eb3\u5347\u7ea7\u55b7\u96fe\uff1a\u5c06 &lt;5 uL \u6325\u53d1\u6027\u3001\u53bb\u76d0\u7f13\u51b2\u6db2\u52a0\u5165\u5bfc\u7535\u55b7\u9488\uff0c\u901a\u8fc7\u6bdb\u7ec6\u4f5c\u7528\u4ee5 &lt;50 nL\/min \u7684\u901f\u5ea6\u76f4\u63a5\u9001\u5165 MS \u5165\u53e3\uff0c\u5e76\u4e14\u7531\u4e8e\u5206\u6790\u7269\u4ece\u672a\u63a5\u89e6\u8272\u8c31\u67f1\uff0c\u8106\u5f31\u590d\u5408\u7269\u80fd\u4fdd\u6301\u8db3\u591f\u65f6\u95f4\u4ee5\u5b9e\u73b0\u9ad8\u5206\u8fa8\u7387\u8d28\u8c31\u5206\u6790\u3002NanoSpray Flex \u79bb\u5b50\u6e90\u914d\u5408 \u79bb\u7ebfNano Electrospray \u5957\u4ef6\uff0c\u4f7f\u96be\u4ee5\u5206\u6790\u7684\u539f\u4f4d\u5e94\u7528\u4e5f\u80fd\u517c\u5bb9\u5148\u8fdb\u8d28\u8c31\u6280\u672f\u3002\u4f8b\u5982\uff0c\u5b83\u5e38\u4e0e Thermo Scientific Q&nbsp;Exactive UHMR \u8d28\u8c31\u4eea\u53ca Thermo Scientific Orbitrap Ascend Structural Biology Tribrid \u8d28\u8c31\u4eea\u8054\u7528\u3002<br><br>\u9759\u6001\u7eb3\u5347\u7ea7\u55b7\u96fe\u7a81\u663e\u4e86\u9009\u62e9\u5408\u9002\u79bb\u5b50\u6e90\u53ca\u76f8\u5173\u914d\u4ef6\u5982\u4f55\u5f00\u8f9f\u65b0\u7684\u5206\u6790\u5e94\u7528\u7a7a\u95f4\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-5-\u4f4e\u6d41\u901f-nbsp-esi-\u7684\u75db\u70b9\u53ca\u5176\u91cd\u8981\u6027\"><strong>5. \u4f4e\u6d41\u901f&nbsp;ESI \u7684\u75db\u70b9\u53ca\u5176\u91cd\u8981\u6027<\/strong><\/h3>\n\n\n\n<p>\u7eb3\u6d41\u548c\u6bdb\u7ec6\u6d41\u7535\u55b7\u96fe\u79bb\u5b50\u5316\uff08ESI\uff09\u80fd\u591f\u63d0\u4f9b\u6781\u9ad8\u7684\u7075\u654f\u5ea6\uff0c\u4f46\u5373\u4f7f\u662f\u7ecf\u9a8c\u4e30\u5bcc\u7684\u7528\u6237\u4e5f\u53ef\u80fd\u611f\u5230\u56f0\u6270\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u55b7\u9488<\/strong><strong>\u5bf9\u51c6<\/strong>\u4f9d\u8d56\u64cd\u4f5c\u4eba\u5458<\/li>\n\n\n\n<li><strong>\u8272\u8c31<\/strong>\u67f1\u3001\u8fde\u63a5\u70b9\u548c\u55b7\u9488\u4e4b\u95f4\u7684\u6b7b\u4f53\u79ef\u4f1a\u5bfc\u81f4\u5cf0\u5f62\u53d8\u5bbd<\/li>\n\n\n\n<li><strong>\u55b7\u9488<\/strong><strong>\u78e8\u635f<\/strong>\u9700\u8981\u9891\u7e41\u66f4\u6362\u548c\u91cd\u65b0\u8c03\u8282<\/li>\n<\/ul>\n\n\n\n<p>\u5bf9\u4e8e\u5927\u89c4\u6a21\u7814\u7a76\u548c\u9700\u8981\u6301\u7eed\u8d28\u8c31\u8fd0\u884c\u7684\u5b9e\u9a8c\u5ba4\uff0c\u8fd9\u79cd\u4e0d\u7a33\u5b9a\u6027\u4f1a\u5bfc\u81f4\u6837\u54c1\u4e22\u5931\u3001\u5b9a\u91cf\u7ed3\u679c\u4e0d\u4e00\u81f4\u4ee5\u53ca\u989d\u5916\u7684\u8d28\u91cf\u63a7\u5236\u5de5\u4f5c\u91cf\u589e\u52a0\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/admin.acceleratingscience.com\/analyteguru\/wp-content\/uploads\/sites\/25\/2026\/02\/Optispray-800x800-1.jpeg\" alt=\"Optispray machine\" class=\"wp-image-19839\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-6-\u98a0\u8986\u6027\u6280\u672f\u767b\u573a-\u8d5b\u9ed8\u98deoptispray\u6280\u672f\u5b9e\u73b0\u7eb3\u6d41\u548c\u6bdb\u7ec6\u6d41esi\u7684\u81ea\u52a8\u5316\u6210\u529f\"><strong>6. \u98a0\u8986\u6027\u6280\u672f\u767b\u573a\uff1a\u8d5b\u9ed8\u98deOptiSpray\u6280\u672f\u5b9e\u73b0\u7eb3\u6d41\u548c\u6bdb\u7ec6\u6d41ESI\u7684\u81ea\u52a8\u5316\u6210\u529f<\/strong><\/h3>\n\n\n\n<p>\u5728ASMS 2025\u4e0a\u53d1\u5e03\u7684OptiSpray\u6280\u672f\u2014\u2014\u5305\u62ecThermo Scientific OptiSpray\u79bb\u5b50\u6e90\u548cThermo Scientific OptiSpray\u5361\u5323\u2014\u2014\u76f4\u9762\u8fd9\u4e9b\u6311\u6218\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7535\u52a8\u4e09\u7ef4\u81ea\u52a8\u5bf9\u51c6\uff1a<strong>\u8fd0\u884c\u201c\u5feb\u901f\u201d\uff08&lt;3\u5206\u949f\uff09\u6216\u201c\u5b8c\u6574\u201d\u4f18\u5316\u7a0b\u5e8f\uff0c\u5c06\u55b7\u96fe<\/strong><strong>\u7cbe\u51c6\u5bf9\u51c6\u8fdb\u6837\u53e3<\/strong><strong>\u2014\u2014\u65e0\u9700\u5c3a\u5b50\uff0c\u65e0\u9700\u731c\u6d4b\uff0c\u65e0\u8bba\u8c01\u5b89\u88c5\u8272\u8c31\u67f1\u90fd\u80fd\u83b7\u5f97\u76f8\u540c\u7ed3\u679c\u3002<\/strong><\/li>\n\n\n\n<li>\u57fa\u4e8e\u5361\u5323\u5f0f\u4e00\u4f53\u5316\u8bbe\u8ba1\u7684\u7b80\u6613\u5b89\u88c5\uff1a<strong>\u96c6\u6210\u8272\u8c31\u67f1\u3001\u8fde\u63a5\u5934\u548c\u55b7<\/strong><strong>\u9488<\/strong><strong>\u4e8e\u4e00\u4f53\u3002\u53ef\u9009\u62e9Thermo Scientific EASY-Spray PepMap Neo UHPLC\u8272\u8c31\u67f1\u6216Thermo Scientific <\/strong><strong>\u03bc<\/strong><strong>PAC Neo HPLC\u8272\u8c31\u67f1\u2014\u2014\u53ea\u9700\u63d2\u5165\u5361<\/strong><strong>\u5323<\/strong><strong>\uff0c<\/strong><strong>\u4e0b\u538b<\/strong><strong>\u624b\u67c4\uff0c\u70b9\u51fb\u4e00\u6b21\uff0c\u5373\u53ef\u5b8c\u6210\u7ba1\u8def\u8fde\u63a5\u3002<\/strong><\/li>\n\n\n\n<li>\u9002\u7528\u4e8e\u6bdb\u7ec6\u6d41\u6216\u7eb3\u6d41\u7684\u55b7\u9488\u9009\u9879\uff1a<\/li>\n\n\n\n<li><strong>\u4e00\u79cd\u4e3a\u9525\u5f62\u8bbe\u8ba1\uff0c\u9002\u7528\u4e8e\u6bdb\u7ec6<\/strong><strong>\u6d41<\/strong><strong>\uff1b\u53e6\u4e00\u79cd\u4e3a\u62c9\u5236\u578b\u8bbe\u8ba1\uff0c\u9002\u7528\u4e8e\u7eb3\u6d41\u901f\u7387\u3002<\/strong><\/li>\n\n\n\n<li>\u55b7\u9488\u4e0e\u55b7\u96fe\u53ef\u89c6\u5316\uff1a<strong>\u63d0\u4f9b\u5bf9\u55b7\u96fe\u7a33\u5b9a\u6027\u7684\u4fe1\u5fc3\uff0c\u5e76\u53ef\u89c2\u5bdf\u5230\u55b7\u96fe\u6270\u52a8\u60c5\u51b5\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u5e73\u53f0\u517c\u5bb9\u6027<\/strong><strong>\uff1a<\/strong>OptiSpray\u79bb\u5b50\u6e90\u53ef\u76f4\u63a5\u5b89\u88c5\u5728Thermo Scientific Orbitrap Astral MS\u7cfb\u5217\u3001Thermo Scientific Orbitrap Tribrid MS\u7cfb\u5217\u3001Thermo Scientific Orbitrap Exploris MS\u7cfb\u5217\u3001Thermo Scientific Orbitrap Excedion Pro MS\u4ee5\u53caThermo Scientific Stellar MS\u4e0a\uff0c\u5e76\u53ef\u4e0eThermo Scientific FAIMS Pro Duo\u63a5\u53e3\u65e0\u7f1d\u914d\u5408\u2014\u2014\u81ea\u52a8\u5bf9\u51c6\u529f\u80fd\u4f1a\u4e3a\u60a8\u627e\u5230FAIMS Pro Duo\u63a5\u53e3\u524d\u55b7\u9488\u7684\u201c\u6700\u4f73\u4f4d\u7f6e\u201d\u3002<\/li>\n\n\n\n<li><strong>\u5bbd\u6d41\u901f<\/strong><strong>\u8303\u56f4<\/strong>(50 nl \u2013 10 uL\/min)\u610f\u5473\u7740\u4e00\u4e2a\u79bb\u5b50\u6e90\u5373\u53ef\u8986\u76d6\u7ea6300 nl\/min\u7684\u7eb3\u6d41DIA\u548c\u51e0\u5fae\u5347\u6bcf\u5206\u949f\u7684\u9ad8\u901a\u91cfPRM\u3002<\/li>\n\n\n\n<li><strong>\u7ecf\u8fc7\u9a8c\u8bc1\u7684\u7a33\u5065\u6027<\/strong><strong>\uff1a<\/strong>\u65e9\u671f\u7a33\u5065\u6027\u6570\u636e\u663e\u793a\uff0c\u5728&gt;2,000\u6b21HeLa\u6d88\u5316\u6db2\u8fdb\u6837\u4e2d\uff0c\u80bd\u6bb5\u9274\u5b9a\u7684CV\u5c0f\u4e8e10%\u3002<\/li>\n<\/ul>\n\n\n\n<p>OptiSpray\u6280\u672f\u5982\u4f55\u5e2e\u52a9\uff1a\u81ea\u52a8\u5316\u55b7\u9488\u5b9a\u4f4d\u8ba9\u65b0\u624b\u548c\u6709\u7ecf\u9a8c\u7528\u6237\u5904\u4e8e\u540c\u4e00\u8d77\u8dd1\u7ebf\uff0c\u51cf\u5c11\u57f9\u8bad\u65f6\u95f4\u5e76\u6d88\u9664\u4eba\u4e3a\u5f15\u5165\u7684\u53d8\u5f02\u3002\u6b64\u5916\uff0c\u5bc6\u5c01\u5f0f\u5361\u5323\u8bbe\u8ba1\u9632\u6b62\u4ea4\u53c9\u6c61\u67d3\u548c\u6b7b\u4f53\u79ef\u4e0d\u4e00\u81f4\u7684\u95ee\u9898\u3002\u7ed3\u679c\u662f\u53ef\u91cd\u590d\u7684\u4f4e\u6d41\u901f\u6570\u636e\u8f93\u51fa\uff0c\u65e0\u8bba\u8c01\u5b89\u88c5\u8272\u8c31\u67f1\uff0c\u90fd\u80fd\u6279\u6b21\u7a33\u5b9a\u3001\u5b9e\u9a8c\u5ba4\u95f4\u7ed3\u679c\u4e00\u81f4\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-7-\u91cd\u70b9\u603b\u7ed3\"><strong>7. \u91cd\u70b9\u603b\u7ed3<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u79bb\u5b50\u6e90\u662f\u68c0\u6d4b\u7684\u5b88\u95e8\u4eba\u3002<\/strong>\u9009\u62e9\u771f\u7a7a\u7535\u79bb\u8fd8\u662f\u5927\u6c14\u538b\u7535\u79bb\uff08\u4ee5\u53ca&nbsp;ESI \/ APCI \/ APPI \u7684\u9009\u62e9\uff09\u76f4\u63a5\u51b3\u5b9a\u80fd\u68c0\u6d4b\u5230\u7684\u7269\u8d28\u8303\u56f4\u3002<\/li>\n\n\n\n<li><strong>\u7535\u55b7\u96fe\u662f\u7ec4\u5b66\u7814\u7a76\u7684\u652f\u67f1\u3002<\/strong>\u591a\u7535\u8377\u79bb\u5b50\u4f7f\u5927\u5206\u5b50\u80fd\u591f\u8fdb\u884c\u9ad8\u5206\u8fa8\u7387\u8d28\u8c31\u5206\u6790\uff0c\u8fd9\u4e00\u7a81\u7834\u83b7\u5f97\u4e86\u8bfa\u8d1d\u5c14\u5956\u8ba4\u53ef\uff0c\u5e76\u6210\u4e3a\u4e86\u73b0\u4ee3\u5de5\u4f5c\u6d41\u7a0b\u7684\u57fa\u7840\u3002<\/li>\n\n\n\n<li><strong>OptiSpray<\/strong><strong>\u6280\u672f<\/strong><strong>\u7b80\u5316\u4e86\u4f4e\u6d41\u91cf\u64cd\u4f5c<\/strong><strong>\u3002<\/strong>\u901a\u8fc7\u81ea\u52a8\u5bf9\u51c6\u5e76\u6d88\u9664\u624b\u52a8\u5bf9\u9f50\uff0c\u5b9e\u73b0\u7528\u6237\u548c\u5b9e\u9a8c\u95f4\u4e00\u81f4\u3001\u9ad8\u7075\u654f\u5ea6\u7684\u6570\u636e\u91c7\u96c6\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u5173\u4e8e\u4e3a\u60a8\u7684\u5e94\u7528\u9009\u62e9\u5408\u9002\u7684\u79bb\u5b50\u6e90\u6709\u7591\u95ee\u5417\uff1f<strong><a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/support\/contact-us-cn.html?icid=blog_banner#form\">\u8054\u7cfb\u6211\u4eec<\/a><\/strong>\u6216\u63a2\u7d22ASMS 2025\u8d44\u6e90\u4e2d\u5fc3\uff0c\u83b7\u53d6\u5e94\u7528\u8bf4\u660e\u3001\u5de5\u4f5c\u6d41\u7a0b\u6d77\u62a5\u548c\u5ba2\u6237\u8bc4\u4ef7\u3002<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. \u5728\u8d28\u8c31\u5206\u6790\u4e2d\uff0c\u201c\u79bb\u5b50\u6e90\u201d\u5230\u5e95\u662f\u4ec0\u4e48\uff1f 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