{"id":458,"date":"2026-02-13T06:28:48","date_gmt":"2026-02-13T06:28:48","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/?p=458"},"modified":"2026-04-30T07:53:25","modified_gmt":"2026-04-30T07:53:25","slug":"the-history-of-the-electron-microscope","status":"publish","type":"post","link":"https:\/\/www.thermofisher.cn\/blog\/the-history-of-the-electron-microscope\/","title":{"rendered":"\u7535\u5b50\u663e\u5fae\u955c\u7684\u5386\u53f2\uff1a\u4ece\u5149\u5b66\u663e\u5fae\u955c\u5230\u51b7\u51bb\u7535\u955c"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/promo\/electron-microscopy\/resource-library.html?icid=cn-blog-msd\"><img loading=\"lazy\" decoding=\"async\" width=\"2337\" height=\"402\" src=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/Blog-\u7535\u955cbanner-1-7.jpg\" alt=\"\" class=\"wp-image-1726\" srcset=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/Blog-\u7535\u955cbanner-1-7.jpg 2337w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/Blog-\u7535\u955cbanner-1-7-300x52.jpg 300w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/Blog-\u7535\u955cbanner-1-7-1024x176.jpg 1024w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/Blog-\u7535\u955cbanner-1-7-768x132.jpg 768w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/Blog-\u7535\u955cbanner-1-7-1536x264.jpg 1536w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/Blog-\u7535\u955cbanner-1-7-2048x352.jpg 2048w\" sizes=\"auto, (max-width: 2337px) 100vw, 2337px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p>\u4f60\u6709\u6ca1\u6709\u60f3\u8fc7\u663e\u5fae\u955c\u662f\u5982\u4f55\u88ab\u53d1\u660e\u7684\uff1f\u81ea\u4ece\u51e0\u4e2a\u4e16\u7eaa\u524d\u7b2c\u4e00\u4e2a\u7248\u672c\u95ee\u4e16\u4ee5\u6765\uff0c\u663e\u5fae\u955c\u5df2\u7ecf\u53d6\u5f97\u4e86\u957f\u8db3\u7684\u8fdb\u6b65\uff0c\u79d1\u5b66\u5bb6\u4eec\u73b0\u5728\u80fd\u591f\u53d1\u73b0\u7684\u91cd\u8981\u6210\u679c\u4e5f\u5927\u4e3a\u63d0\u5347\u3002\u7279\u522b\u662f\u51b7\u51bb\u7535\u5b50\u663e\u5fae\u955c\uff08cryo-EM\uff09\u5982\u4eca\u5bf9\u4e8e\u79d1\u5b66\u5bb6\u800c\u8a00\uff0c\u5c31\u5982\u540c\u624b\u672f\u5200\u5bf9\u4e8e\u5916\u79d1\u533b\u751f\u4e00\u6837\uff0c\u662f\u884c\u52a8\u7684\u5de5\u5177\uff0c\u800c\u4e0d\u4ec5\u4ec5\u662f\u89c2\u5bdf\u7684\u5de5\u5177\u3002\u6b63\u5982\u8bfa\u8d1d\u5c14\u5956\u5f97\u4e3b<a href=\"https:\/\/www.smh.com.au\/national\/university-of-sydney-s-4-5m-microscope-will-make-a-huge-difference-in-the-world-20180911-p5031h.html?cid=2019-XBU-AwarenessEM&amp;utm_source=Comms-Blog&amp;utm_medium=EM%20Blog&amp;utm_campaign=2019-XBU-AwarenessEM&amp;utm_term=speak-to-an-expert-9\">\u827e\u4f26\u00b7\u82ac\u514b\u5c14\u535a\u58eb<\/a>\u6240\u8bf4\uff1a\u201c\u6ca1\u6709\u663e\u5fae\u6280\u672f\uff0c\u5c31\u6ca1\u6709\u73b0\u4ee3\u79d1\u5b66\u3002\u201d<\/p>\n\n\n\n<figure class=\"wp-block-image alignnone\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"750\" src=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_4_-10.jpg\" alt=\"Brain cell image obtained with electron microscopy\" class=\"wp-image-463\" srcset=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_4_-10.jpg 1000w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_4_-10-300x225.jpg 300w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_4_-10-768x576.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><figcaption class=\"wp-element-caption\">\u4e00\u5f20\u51b7\u51bb\u7535\u955c\u56fe\u50cf\uff0c\u5c55\u793a\u4e86\u8111\u7ec6\u80de\uff08\u84dd\u8272\uff09\u4e0e\u4eff\u7ec6\u80de\u5916\u73af\u5883\u7684\u5408\u6210\u6750\u6599\uff08\u7eff\u8272\uff09\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u3002<\/figcaption><\/figure>\n\n\n\n<p>\u4eba\u7c7b\u5929\u751f\u5145\u6ee1\u597d\u5947\u5fc3\uff0c\u6211\u4eec\u5bf9\u672a\u77e5\u7684\u8ff7\u604b\u4fc3\u4f7f\u6211\u4eec\u53bb\u63a2\u7d22\u4e00\u4e9b\u751f\u547d\u4e2d\u6700\u56f0\u96be\u7684\u6311\u6218\u3002\u5982\u4eca\u7684<a href=\"https:\/\/www.thermofisher.com\/search\/browse\/category\/us\/en\/90184048\" target=\"_blank\" rel=\"noopener\">\u5148\u8fdb\u663e\u5fae\u955c<\/a>\u5e2e\u52a9\u79d1\u5b66\u5bb6\u4ee5\u4e09\u7ef4\u5f62\u5f0f\u89c2\u5bdf\u75c5\u6bd2\u548c\u86cb\u767d\u8d28\u7684\u7ed3\u6784\u3002\u79d1\u5b66\u5bb6\u73b0\u5728\u5229\u7528\u8fd9\u4e9b\u5148\u8fdb\u663e\u5fae\u955c\u548c\u65b0\u6280\u672f\u6765\u7814\u7a76\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff0c\u5982\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u5e15\u91d1\u68ee\u75c5\u548c\u4ea8\u5ef7\u987f\u821e\u8e48\u75c7\uff0c\u4ee5\u53ca\u764c\u75c7\u3001\u827e\u6ecb\u75c5\u3001\u759f\u75be\u3001\u5be8\u5361\u75c5\u6bd2\u7b49\u8bb8\u591a\u5176\u4ed6\u75be\u75c5\u3002\u66f4\u6df1\u5165\u5730\u4e86\u89e3\u86cb\u767d\u8d28\u548c\u75c5\u6bd2\u7684\u529f\u80fd\uff0c\u6709\u52a9\u4e8e\u7814\u7a76\u4eba\u5458\u52a0\u5feb\u5f00\u53d1\u66f4\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u548c\u7597\u6cd5\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-\u663e\u5fae\u6280\u672f\u7684\u5f00\u7aef\"><strong>\u663e\u5fae\u6280\u672f\u7684\u5f00\u7aef<\/strong><\/h2>\n\n\n\n<p>\u663e\u5fae\u955c\u7684\u53d1\u5c55\u51e0\u4e4e\u662f\u572816\u4e16\u7eaa\u521d\u8be5\u4eea\u5668\u88ab\u53d1\u660e\u540e\u4e0d\u4e45\u5c31\u5f00\u59cb\u4e86\u3002\u5f5316\u4e16\u7eaa\u7684\u79d1\u5b66\u5bb6\u4eec\u5728\u751f\u7269\u5b66\u548c\u5316\u5b66\u9886\u57df\u53d6\u5f97\u8fdb\u5c55\u65f6\uff0c\u4ed6\u4eec\u610f\u8bc6\u5230\u81ea\u5df1\u9700\u8981\u770b\u5230\u8d85\u51fa\u8089\u773c\u6240\u53ca\u7684\u7ec6\u8282\u3002\u4ed6\u4eec\u7684\u89e3\u51b3\u65b9\u6848\u662f\u5229\u7528\u73bb\u7483\u6765\u5f2f\u66f2\u5149\u7ebf\uff0c\u4ece\u800c\u53d1\u660e\u4e86\u653e\u5927\u955c\u3002\u4f46\u5982\u679c\u5c06\u591a\u4e2a\u955c\u7247\u7ec4\u5408\u5728\u4e00\u8d77\u4f1a\u53d1\u751f\u4ec0\u4e48\u5462\uff1f\u572816\u4e16\u7eaa\u672b\uff0c\u4e24\u4f4d\u8377\u5170\u7684\u773c\u955c\u5236\u9020\u5546\u2014\u2014\u624e\u5361\u91cc\u4e9a\u65af\u00b7\u8a79\u68ee\u548c\u4ed6\u7684\u7236\u4eb2\u6c49\u65af\u2014\u2014\u51b3\u5b9a\u4eb2\u81ea\u5c1d\u8bd5\u3002\u4ed6\u4eec\u5c06\u591a\u4e2a\u955c\u7247\u53e0\u653e\u5728\u4e00\u4e2a\u7ba1\u5b50\u91cc\uff0c\u53d1\u73b0\u8fd9\u4e9b\u955c\u7247\u7ec4\u5408\u5728\u4e00\u8d77\u53ef\u4ee5\u4f7f\u7269\u4f53\u770b\u8d77\u6765\u6bd4\u5355\u4e2a\u653e\u5927\u955c\u653e\u5927\u5f97\u591a\u3002\u7531\u4e8e\u6700\u5927\u653e\u5927\u500d\u6570\u4ec5\u4e3a9\u500d\uff0c\u5b83\u4eec\u66f4\u50cf\u662f\u4e00\u79cd\u65b0\u5947\u73a9\u610f\uff0c\u800c\u975e\u79d1\u5b66\u4eea\u5668\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"1572\" height=\"582\" src=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_3_-10.jpg\" alt=\"Early observations performed with microscopy\" class=\"wp-image-462\" srcset=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_3_-10.jpg 1572w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_3_-10-300x111.jpg 300w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_3_-10-1024x379.jpg 1024w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_3_-10-768x284.jpg 768w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_3_-10-1536x569.jpg 1536w\" sizes=\"auto, (max-width: 1572px) 100vw, 1572px\" \/><figcaption class=\"wp-element-caption\">1825\u5e74\uff0c\u5b89\u4e1c\u5c3c\u00b7\u8303\u00b7\u5217\u6587\u864e\u514b\u5bf9\u65e9\u671f\u663e\u5fae\u955c\u89c2\u5bdf\u81ea\u7136\u7684\u7d20\u63cf\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u5b89\u4e1c\u5c3c\u00b7\u8303\u00b7\u5217\u6587\u864e\u514b\uff0c\u8fd9\u4f4d\u8377\u5170\u79d1\u5b66\u5bb6\u3001\u663e\u5fae\u955c\u5b66\u7684\u5148\u9a71\u4e4b\u4e00\uff0c\u6210\u4e3a\u7b2c\u4e00\u4e2a\u4e3a\u79d1\u5b66\u76ee\u7684\u5236\u9020\u5e76\u4f7f\u7528\u663e\u5fae\u955c\u7684\u4eba\u3002\u4ed6\u624b\u5de5\u5236\u4f5c\u7684\u5355\u955c\u7247\u663e\u5fae\u955c\u662f\u901a\u8fc7\u7814\u78e8\u5e76\u629b\u5149\u73bb\u7483\u7403\u5236\u6210\u66f2\u9762\u955c\u7247\u7684\uff0c\u4ed6\u53d1\u73b0\u8fd9\u79cd\u66f2\u9762\u4f7f\u4ed6\u80fd\u5c06\u7269\u4f53\u653e\u5927\u5230\u8089\u773c\u6240\u89c1\u7684270\u500d\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u4f7f\u7528\u5e73\u9762\u955c\u7247\u7684\u663e\u5fae\u955c\u53ea\u80fd\u653e\u5927\u523050\u500d\u3002\u4ed6\u7528\u65b0\u7684\u663e\u5fae\u955c\u5206\u6790\u6606\u866b\uff0c\u5e76\u6700\u7ec8\u53d1\u73b0\u4e86\u7ec6\u83cc\uff0c\u56e0\u6b64\u88ab\u8a89\u4e3a\u201c\u663e\u5fae\u955c\u4e4b\u7236\u201d\u3002<\/p>\n\n\n\n<p>\u4e3a\u4e86\u63d0\u5347\u5355\u955c\u7247\u663e\u5fae\u955c\u7684\u80fd\u529b\uff0c\u79d1\u5b66\u5bb6\u5fc5\u987b\u627e\u5230\u4e00\u79cd\u65b9\u6cd5\uff0c\u5728\u4fdd\u6301\u955c\u7247\u76f4\u5f84\u7684\u540c\u65f6\u51cf\u5c11\u663e\u5fae\u955c\u7684\u7126\u8ddd\u3002\u5982\u679c\u955c\u7247\u505a\u5f97\u592a\u5c0f\uff0c\u5c06\u96be\u4ee5\u89c2\u5bdf\uff0c\u56fe\u50cf\u4e5f\u53ef\u80fd\u53d8\u5f97\u6a21\u7cca\u3002\u89e3\u51b3\u65b9\u6848\u662f\uff1a\u590d\u5408\u663e\u5fae\u955c\u3002<\/p>\n\n\n\n<p>A <a href=\"https:\/\/www.thermofisher.com\/search\/browse\/category\/us\/en\/90184106\" target=\"_blank\" rel=\"noopener\">\u590d\u5408\u663e\u5fae\u955c<\/a>\u4f7f\u7528\u4e24\u4e2a\u6216\u591a\u4e2a\u955c\u7247\u5c06\u56fe\u50cf\u653e\u5927\u5230\u66f4\u9ad8\u7684\u500d\u6570\u3002\u5176\u57fa\u672c\u7ed3\u6784\u7531\u4e24\u4e2a\u90e8\u5206\u7ec4\u6210\uff1a<\/p>\n\n\n\n<ol 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id=\"h-\u900f\u5c04\u7535\u5b50\u663e\u5fae\u955c-tem-\u662f\u5982\u4f55\u88ab\u53d1\u660e\u7684\"><span lang=\"EN-US\"><strong>\u900f\u5c04\u7535\u5b50\u663e\u5fae\u955c\uff08TEM\uff09\u662f\u5982\u4f55\u88ab\u53d1\u660e\u7684<\/strong> <\/span><\/h2>\n\n\n\n<p>1900\u5e74\uff0c\u5149\u5b66\u663e\u5fae\u955c\u8fbe\u5230\u4e86\u7406\u8bba\u4e0a\u7684\u5206\u8fa8\u7387\u6781\u9650\u3002\u7269\u7406\u5b66\u539f\u7406\u51b3\u5b9a\u4e86\u5149\u5b66\u663e\u5fae\u955c\u7684\u653e\u5927\u500d\u6570\u53ea\u80fd\u5728500\u500d\u52301,000\u500d\u4e4b\u95f4\uff0c\u5206\u8fa8\u7387\u8fbe\u52300.2\u5fae\u7c73\uff082,000\u57c3\uff09\u3002\u56db\u5e74\u540e\uff0c\u5361\u5c14\u00b7\u8521\u53f8\uff08Carl 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Knoll\uff09\u627e\u5230\u4e86\u4e00\u79cd\u5b9e\u73b0\u6bd4\u5149\u66f4\u9ad8\u5206\u8fa8\u7387\u7684\u65b9\u6cd5\u3002\u4ed6\u4eec\u53d1\u73b0\u53ef\u4ee5\u901a\u8fc7\u6837\u54c1\u4f20\u8f93\u7535\u5b50\u6765\u5f62\u6210\u56fe\u50cf\u3002\u8fd9\u4e00\u53d1\u73b0\u4fc3\u6210\u4e86\u7b2c\u4e00\u53f0\u900f\u5c04\u7535\u5b50\u663e\u5fae\u955c\uff08TEM\uff09\uff0c\u5728\u8be5\u663e\u5fae\u955c\u4e2d\uff0c\u7535\u5b50\u76f4\u63a5\u5c04\u5411\u6837\u54c1\u5e76\u7a7f\u900f\u5b83\u4ee5\u751f\u6210\u56fe\u50cf\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center\"><!--[endif]--><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"1438\" height=\"1428\" src=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_2_-10.jpg\" alt=\"TEM image of grass shrimp embryo\" class=\"wp-image-464\" srcset=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_2_-10.jpg 1438w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_2_-10-300x298.jpg 300w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_2_-10-1024x1017.jpg 1024w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_2_-10-150x150.jpg 150w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_2_-10-768x763.jpg 768w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_2_-10-80x80.jpg 80w\" sizes=\"auto, (max-width: 1438px) 100vw, 1438px\" \/><figcaption class=\"wp-element-caption\">\u900f\u5c04\u7535\u5b50\u663e\u5fae\u955c\u56fe\u50cf\u7684<em>Palaemonetes pugio<\/em>(\u8349\u867e)\u80da\u80ce\u663e\u793a\u80da\u80ce\u5916\u819c\u7684\u53d1\u80b2\u60c5\u51b5\uff0c\u6444\u4e8e1933\u5e74\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"h-\u626b\u63cf\u7535\u5b50\u663e\u5fae\u955c-sem-\u548c\u6570\u5b57\u6210\u50cf\u7684\u5174\u8d77\"><strong>\u626b\u63cf\u7535\u5b50\u663e\u5fae\u955c\uff08SEM\uff09\u548c\u6570\u5b57\u6210\u50cf\u7684\u5174\u8d77<\/strong><\/h2>\n\n\n\n<p>\u5341\u5e74\u540e\uff0c\u9c81\u65af\u5361\u91c7\u7528\u4e86\u4e00\u79cd\u7c7b\u4f3c\u4f46\u4e0d\u540c\u7684\u65b9\u6cd5\uff0c\u4f7f\u7528\u805a\u7126\u7684\u7535\u5b50\u675f\u4ee5\u77e9\u5f62\u6a21\u5f0f\u626b\u63cf\u6837\u54c1\u8868\u9762\uff0c\u4ee5\u63d0\u4f9b\u6709\u5173\u5176\u8868\u9762\u5f62\u8c8c\u548c\u6210\u5206\u7684\u4fe1\u606f\u3002\u4e0eTEM\u4e0d\u540c\uff0c\u8fd9\u79cd\u65b0\u578b\u626b\u63cf\u7535\u5b50\u663e\u5fae\u955c\uff08SEM\uff09\u7684\u56fe\u50cf\u662f\u5728\u663e\u5fae\u955c\u6536\u96c6\u5e76\u8ba1\u6570\u6563\u5c04\u7535\u5b50\u540e\u5f62\u6210\u7684\u3002<\/p>\n\n\n\n<p>1986\u5e74\uff0c\u65e5\u672c\u79d1\u5b66\u5bb6\u63a8\u51fa\u4e86\u6570\u5b57\u663e\u5fae\u955c\uff0c\u8bb8\u591a\u4eba\u8ba4\u4e3a\u8fd9\u5f7b\u5e95\u6539\u53d8\u4e86\u663e\u5fae\u6280\u672f\u3002\u4ed6\u4eec\u5f00\u53d1\u4e86\u4e00\u79cd\u5c06\u663e\u5fae\u955c\u4e0b\u7684\u56fe\u50cf\u4f20\u8f93\u5230\u8ba1\u7b97\u673a\u4e0a\u4ee5\u4fbf\u5373\u65f6\u5206\u6790\u7684\u65b9\u6cd5\u3002\u5982\u4eca\uff0c\u663e\u5fae\u955c\u914d\u5907\u4e86\u5185\u7f6e\u9ad8\u6e05\u663e\u793a\u5668\uff0c\u65e0\u9700\u5916\u90e8\u8ba1\u7b97\u673a\u5373\u53ef\u67e5\u770b\u56fe\u50cf\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-\u51b7\u51bb\u7535\u5b50\u663e\u5fae\u955c-cryo-em-\u548c\u4e09\u7ef4\u7ed3\u6784\u5206\u6790\u7684\u7a81\u7834\"><strong>\u51b7\u51bb\u7535\u5b50\u663e\u5fae\u955c\uff08cryo-EM\uff09\u548c\u4e09\u7ef4\u7ed3\u6784\u5206\u6790\u7684\u7a81\u7834<\/strong><\/h2>\n\n\n\n<p>\u5373\u4f7f\u5230\u4e86\u8fd1\u5e74\uff0c\u663e\u5fae\u6280\u672f\u9762\u4e34\u7684\u4e3b\u8981\u6311\u6218\u4ecd\u7136\u662f\u5982\u4f55\u5c06\u6a21\u7cca\u7684\u4e8c\u7ef4\u56fe\u50cf\u91cd\u5efa\u4e3a\u6e05\u6670\u7684\u4e09\u7ef4\u7ed3\u6784\u3002\u5728\u8fd1\u4e8c\u5341\u5e74\u7684\u65f6\u95f4\u91cc\uff0c\u4e09\u4f4d\u7814\u7a76\u4eba\u5458\u2014\u2014\u96c5\u514b\u00b7\u675c\u535a\u6b47\uff08Jacques Dubochet\uff09\u3001\u7ea6\u963f\u5e0c\u59c6\u00b7\u5f17\u5170\u514b\uff08Joachim Frank\uff09\u548c\u7406\u67e5\u5fb7\u00b7\u4ea8\u5fb7\u68ee\uff08Richard Henderson\uff09\u2014\u2014\u5f00\u53d1\u51fa\u4e86\u4e00\u79cd\u5229\u7528\u7535\u5b50\u663e\u5fae\u955c\u5728\u539f\u5b50\u5c42\u9762\u751f\u6210\u86cb\u767d\u8d28\u4e09\u7ef4\u7ed3\u6784\u7684\u6280\u672f\u3002\u4ed6\u4eec\u7684\u6280\u672f\u4f7f\u7528\u73bb\u7483\u5316\u65b9\u6cd5\u5c06\u6837\u54c1\u51b7\u5374\u81f3\u4f4e\u6e29\uff0c\u4ece\u800c\u4f7f\u751f\u7269\u5206\u5b50\u5728\u771f\u7a7a\u4e2d\u4fdd\u6301\u5176\u5f62\u72b6\u3002\u8fd9\u79cd\u65b9\u6cd5\u88ab\u79f0\u4e3a\u51b7\u51bb\u7535\u5b50\u663e\u5fae\u955c\uff08cryo-electron microscopy\uff0c\u7b80\u79f0cryo-EM\uff09\u3002<a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/electron-microscopy\/life-sciences\/cryo-em.html\">\u51b7\u51bb\u7535\u5b50\u663e\u5fae\u955c\uff08cryo-EM\uff09<\/a>\u8363\u83b72017\u5e74\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_1_-10.jpg\" alt=\"Carbon nanotube observed with TEM\" class=\"wp-image-465\" srcset=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_1_-10.jpg 1000w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_1_-10-300x300.jpg 300w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_1_-10-150x150.jpg 150w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_1_-10-768x768.jpg 768w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/02\/history20of20microscope20_1_-10-80x80.jpg 80w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><figcaption class=\"wp-element-caption\">\u4f7f\u7528Thermo Scientific\u2122 Krios\u2122 3Gi Cryo-TEM\u4ece\u94b4\u94c1\u6c27\u4f53\u7eb3\u7c73\u9897\u7c92\u83b7\u5f97\u7684\u78b3\u7eb3\u7c73\u7ba1\u751f\u6210\u56fe\u50cf\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u56de\u987e\u8fc7\u53bb\uff0c\u663e\u5fae\u955c\u5df2\u7ecf\u7ecf\u5386\u4e86\u6f2b\u957f\u7684\u53d1\u5c55\u5386\u7a0b\u3002\u4ece\u5355\u955c\u5934\u653e\u5927\u955c\u5230<a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/electron-microscopy\/products.html\">\u5f53\u4eca\u5e9e\u5927\u7684\u7535\u5b50\u663e\u5fae\u955c<\/a>\uff0c\u8fd9\u9879\u6280\u672f\u6b63\u5728\u6539\u53d8\u79d1\u5b66\u3002\u7531\u4e8e\u663e\u5fae\u955c\u6280\u672f\u7684\u8fdb\u6b65\uff0c\u6211\u4eec\u73b0\u5728\u80fd\u591f\u89c2\u5bdf\u5230\u539f\u5b50\u7ea7\u522b\u7684\u6837\u672c\uff0c\u653e\u5927\u500d\u6570\u53ef\u8fbe\u4eba\u773c\u76841000\u4e07\u500d\u4ee5\u4e0a\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f60\u6709\u6ca1\u6709\u60f3\u8fc7\u663e\u5fae\u955c\u662f\u5982\u4f55\u88ab\u53d1\u660e\u7684\uff1f\u81ea\u4ece\u51e0\u4e2a\u4e16\u7eaa\u524d\u7b2c\u4e00\u4e2a\u7248\u672c\u95ee\u4e16\u4ee5\u6765\uff0c\u663e\u5fae\u955c\u5df2\u7ecf\u53d6\u5f97\u4e86\u957f\u8db3\u7684\u8fdb\u6b65\uff0c\u79d1\u5b66\u5bb6\u4eec\u73b0\u5728\u80fd<\/p>\n","protected":false},"author":1852,"featured_media":459,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[7],"tags":[33,20],"division":[6],"class_list":{"0":"post-458","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-7","8":"tag-33","9":"tag-20","10":"division-msd","11":"entry"},"_selected_authors":[1292],"_selected_reviewers":[],"acf":[],"yoast_head":"<!-- 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