{"id":751,"date":"2026-03-09T09:05:05","date_gmt":"2026-03-09T09:05:05","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/?p=751"},"modified":"2026-05-13T02:50:14","modified_gmt":"2026-05-13T02:50:14","slug":"cad-vs-elsd-which-hplc-detector-is-your-better-option","status":"publish","type":"post","link":"https:\/\/www.thermofisher.cn\/blog\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/","title":{"rendered":"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/industrial\/chromatography\/download-solution.html?icid=cn-blog-cmd\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"176\" src=\"http:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/04\/779-\u00d7-134-CMD-1024x176.jpg\" alt=\"\" class=\"wp-image-1799\" srcset=\"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/04\/779-\u00d7-134-CMD-1024x176.jpg 1024w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/04\/779-\u00d7-134-CMD-300x52.jpg 300w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/04\/779-\u00d7-134-CMD-768x132.jpg 768w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/04\/779-\u00d7-134-CMD-1536x264.jpg 1536w, https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/04\/779-\u00d7-134-CMD-2048x352.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<p>\u5728 HPLC\/UHPLC \u5206\u6790\u4e2d\uff0c\u6700\u5e38\u7528\u7684\u68c0\u6d4b\u5668\u662f UV-Vis\uff08\u7d2b\u5916-\u53ef\u89c1\uff09\u68c0\u6d4b\u5668\u3002\u4f46\u5982\u679c\u4f60\u7684\u5206\u6790\u7269\u6ca1\u6709\u53d1\u8272\u56e2\u3001\u65e0\u6cd5\u7528 UV-Vis \u68c0\u6d4b\uff0c\u53c8\u8be5\u600e\u4e48\u529e\uff1f<\/p>\n\n\n\n<p>\u4f60\u5f88\u53ef\u80fd\u4f1a\u8f6c\u5411\u66f4\u201c\u901a\u7528\u201d\u7684\u68c0\u6d4b\u5668\uff0c\u4f8b\u5982\u8377\u7535\u6c14\u6eb6\u80f6\u68c0\u6d4b\u5668\uff08CAD\uff09\u4e0e\u84b8\u53d1\u5149\u6563\u5c04\u68c0\u6d4b\u5668\uff08ELSD\uff09\u3002\u65e0\u8bba\u662f\u5426\u5b58\u5728\u53d1\u8272\u56e2\uff0c\u8fd9\u7c7b\u68c0\u6d4b\u5668\u90fd\u53ef\u6d4b\u91cf\u4e0d\u6325\u53d1\u4ee5\u53ca\u8bb8\u591a\u534a\u6325\u53d1\u5316\u5408\u7269\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/admin.acceleratingscience.com\/analyteguru\/wp-content\/uploads\/sites\/25\/2024\/02\/HPIC-022024-1200-1024x806.jpg\" alt=\"CAD vs ELSD\" class=\"wp-image-17090\" \/><\/figure>\n<\/div>\n\n\n<p>CAD\u548cELSD\u90fd\u662f\u84b8\u53d1\u5f0f\u6c14\u6eb6\u80f6\u68c0\u6d4b\u5668\uff0c\u5b83\u4eec\u6839\u636e\u76f8\u5bf9\u6325\u53d1\u6027\u533a\u5206\u5206\u6790\u7269\u4e0e\u6d41\u52a8\u76f8\u3002\u56e0\u6b64\uff0c\u4e24\u8005\u5177\u6709\u7c7b\u4f3c\u7684\u68c0\u6d4b\u8303\u56f4\uff08\u975e\u6325\u53d1\u6027\u548c\u534a\u6325\u53d1\u6027\u5206\u6790\u7269\uff09\uff0c\u5e76\u4e14\u57fa\u672c\u64cd\u4f5c\u8981\u6c42\u76f8\u540c\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4f7f\u7528\u9ad8\u8d28\u91cf\u3001\u5728\u84b8\u53d1\u540e\u6b8b\u7559\u6781\u5c11\u7684\u6325\u53d1\u6027\u6d41\u52a8\u76f8\u53ca\u6dfb\u52a0\u5242<\/li>\n\n\n\n<li>\u6301\u7eed\u4f9b\u5e94\u7eaf\u51c0\u6c14\u4f53\uff0c\u901a\u5e38\u4e3a\u6c2e\u6c14<\/li>\n\n\n\n<li>\u7a33\u5b9a\u4e14\u65e0\u6e17\u6f0f\u7684\u8272\u8c31\u67f1<\/li>\n<\/ul>\n\n\n\n<p>\u5982\u679c\u4f60\u5bf9\u8fd9\u4e2a\u8bdd\u9898\u4e0d\u964c\u751f\uff0c\u53ef\u80fd\u5df2\u7ecf\u77e5\u9053\u8272\u8c31\u5708\u957f\u671f\u5b58\u5728\u201cCAD \u4e0e ELSD \u54ea\u4e2a\u66f4\u597d\u201d\u7684\u4e89\u8bba\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-\u4e0b\u9762\u6211\u4eec\u4ece\u5404\u81ea\u7684\u68c0\u6d4b\u539f\u7406\u51fa\u53d1-\u8fdb\u4e00\u6b65\u770b\u770b\u5dee\u5f02\"><strong><strong><strong>\u4e0b\u9762\u6211\u4eec\u4ece\u5404\u81ea\u7684\u68c0\u6d4b\u539f\u7406\u51fa\u53d1\uff0c\u8fdb\u4e00\u6b65\u770b\u770b\u5dee\u5f02\u3002<\/strong><\/strong><\/strong><\/h3>\n\n\n\n<p>\u8377\u7535\u6c14\u6eb6\u80f6\u7684\u6d4b\u91cf\u5728\u539f\u7406\u5c42\u9762\u3001\u5e76\u4e14\u5728\u5b9e\u9645\u8868\u73b0\u4e0a\uff0c\u901a\u5e38\u6bd4\u5149\u6563\u5c04\u66f4\u7075\u654f\uff0c\u8fd9\u4f1a\u663e\u8457\u5f71\u54cd\u6574\u4f53\u5206\u6790\u6027\u80fd\u3002<\/p>\n\n\n\n<p>\u539f\u56e0\u5982\u4e0b\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5728CAD\u4e2d\uff0c\u9897\u7c92\u901a\u8fc7\u4e0e\u7535\u79bb\u6c2e\u6c14\u78b0\u649e\u83b7\u5f97\u7535\u8377\uff0c\u5e76\u4e14\u5145\u7535\u8fc7\u7a0b\u4e0e\u5316\u5b66\u7ed3\u6784\u65e0\u5173\u3002\u9897\u7c92\u4e0a\u7684\u7535\u8377\u901a\u8fc7\u9ad8\u7075\u654f\u5ea6\u7684\u9759\u7535\u8ba1\u8fdb\u884c\u6d4b\u91cf\uff0c\u4fe1\u53f7\u4e0e\u9897\u7c92\u5927\u5c0f\uff08\u5206\u6790\u7269\u7684\u8d28\u91cf\uff09\u6210\u6b63\u6bd4\u3002\u5206\u6790\u7269\u542b\u91cf\u8d8a\u591a\uff0c\u9897\u7c92\u5c3a\u5bf8\u8d8a\u5927\uff0c\u643a\u5e26\u7684\u7535\u8377\u4e5f\u8d8a\u591a\uff0c\u4ece\u800c\u4ea7\u751f\u66f4\u9ad8\u7684\u54cd\u5e94\u3002<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5bf9\u4e8eELSD\uff0c\u901a\u8fc7\u5e72\u71e5\u6c14\u6eb6\u80f6\u9897\u7c92\u6563\u5c04\u7684\u5149\u6765\u786e\u5b9a\u5206\u6790\u7269\u7684\u542b\u91cf\u3002\u4e0eCAD\u4e00\u6837\uff0c\u4fe1\u53f7\u4e5f\u4e0e\u9897\u7c92\u5927\u5c0f\u6210\u6b63\u6bd4\u3002\u4f46\u8fd9\u79cd\u5173\u7cfb\u8981\u590d\u6742\u5f97\u591a\uff0c\u56e0\u4e3a\u6563\u5c04\u5149\u7684\u5f3a\u5ea6\u4f1a\u6839\u636e\u9897\u7c92\u5927\u5c0f\u5448\u6307\u6570\u53d8\u5316\uff0c\u5bfc\u81f4\u590d\u6742\u7684S\u578b\u54cd\u5e94\u66f2\u7ebf\u3002\u5728ELSD\u4e2d\uff0c\u5bf9\u4e8e\u8f83\u5c0f\u7684\u9897\u7c92\u51e0\u4e4e\u5f97\u4e0d\u5230\u4fe1\u53f7\u6216\u4fe1\u53f7\u6781\u4f4e\uff0c\u5e76\u4e14<a href=\"https:\/\/doi.org\/10.1016\/j.jpba.2009.10.019\"><u>\u5206\u6790\u7269\u95f4\u5c5e\u6027<\/u><\/a>\u2014\u5982\u6298\u5c04\u7387\u3001\u5149\u5438\u6536\u548c\u8367\u5149\u2014\u90fd\u53ef\u80fd\u5f71\u54cd\u54cd\u5e94\u3002<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Why Choose Charged Aerosol Detection for Your HPLC Analysis?\" width=\"760\" height=\"428\" src=\"https:\/\/www.youtube.com\/embed\/jw1q0ldJiRg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>\u56e0\u6b64\uff0c\u5373\u4f7fCAD\u548cELSD\u5177\u6709<a href=\"https:\/\/www.thermofisher.cn\/cn\/zh\/home\/industrial\/chromatography\/chromatography-learning-center\/liquid-chromatography-information\/hplc-system-components\/how-hplc-detectors-work\/charged-aerosol-detection\/charged-aerosol-detection-benefits.html\"><u>\u529f\u80fd\u4e0a\u7684\u76f8\u4f3c\u6027<\/u><\/a>\uff0c\u68c0\u6d4b\u5668\u6d4b\u91cf\u5206\u6790\u7269\u8d28\u91cf\u7684\u673a\u5236\u5374\u6709\u663e\u8457\u4e0d\u540c\u3002\u5982\u6587\u732e\u6240\u793a\uff0c\u5728\u52a8\u6001\u8303\u56f4\u3001\u7ebf\u6027\u8303\u56f4\u3001\u7075\u654f\u5ea6\u3001\u7cbe\u5bc6\u5ea6\u548c\u51c6\u786e\u6027\u65b9\u9762\uff0cCAD\u5f80\u5f80\u4f18\u4e8eELSD\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-cad\u4f18\u4e8eelsd\u7684\u4e3b\u8981\u65b9\u5f0f-1-23-\u6709\u5df2\u53d1\u8868\u7684\u6570\u636e\u652f\u6301\"><strong><strong>CAD\u4f18\u4e8eELSD\u7684\u4e3b\u8981\u65b9\u5f0f<sup>1-23<\/sup>\u6709\u5df2\u53d1\u8868\u7684\u6570\u636e\u652f\u6301<\/strong><\/strong><\/h3>\n\n\n\n<p><strong><strong>1. \u4ece\u5b9e\u9645\u89d2\u5ea6\u6765\u770b\uff0cCAD\u7684\u68c0\u6d4b\u9650\u6bd4ELSD\u9ad8\u51fa10\u500d\u6216\u66f4\u591a<\/strong><\/strong><\/p>\n\n\n\n<p>\u8fd9\u79cd\u5728\u62a5\u544a\u4e2d\u7684\u5b9a\u91cf\u5dee\u5f02<a href=\"https:\/\/doi.org\/10.1016\/j.talanta.2016.01.027\"><u>\u68c0\u6d4b\u9650<\/u><\/a>(LOD) \u4e24\u79cd\u68c0\u6d4b\u5668\u4e4b\u95f4\u7684\u5dee\u5f02\u6e90\u4e8e\u9897\u7c92\u5927\u5c0f\u3002<\/p>\n\n\n\n<p>CAD\u7684\u7075\u654f\u5ea6\u8fdc\u9ad8\u4e8eELSD\uff0c\u56e0\u4e3a\u5b83\u53ef\u4ee5\u5b9a\u91cf\u68c0\u6d4b\u66f4\u5c0f\u7684\u9897\u7c92\uff08\u66f4\u5c11\u91cf\u7684\u5206\u6790\u7269\uff09\u3002\u5bf9\u4e8eELSD\uff0c\u9897\u7c92\u5fc5\u987b\u8db3\u591f\u5927\u624d\u80fd\u6709\u6548\u6563\u5c04\u5149\uff0c\u5bf9\u4e8e\u76f4\u5f84\u5c0f\u4e8e\u7ea650\u7eb3\u7c73\u7684\u9897\u7c92\u51e0\u4e4e\u6ca1\u6709\u4fe1\u53f7\u3002<\/p>\n\n\n\n<p>\u4e0eELSD\u4e0d\u540c\uff0cCAD\u5bf9\u76f4\u5f84\u4ec5\u4e3a10\u7eb3\u7c73\u7684\u9897\u7c92\u4ecd\u80fd\u4fdd\u6301\u826f\u597d\u7684\u7075\u654f\u5ea6\u3002<\/p>\n\n\n\n<p><strong><strong>2. CAD\u672c\u8eab\u5177\u6709\u66f4\u5bbd\u7684\u52a8\u6001\u8303\u56f4\uff0c\u901a\u5e38\u662fELSD\u7684\u4e24\u500d<\/strong><\/strong><\/p>\n\n\n\n<p>\u5f53\u9700\u8981\u5728\u9ad8\u6d53\u5ea6\u53e6\u4e00\u79cd\u7269\u8d28\u5b58\u5728\u65f6\u6d4b\u91cf\u4f4e\u6d53\u5ea6\u5206\u6790\u7269\u65f6\uff0c\u5bbd\u52a8\u6001\u8303\u56f4\u81f3\u5173\u91cd\u8981\uff0c\u4f8b\u5982<a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10408347.2023.2291815\"><u>\u6742\u8d28\u5206\u6790<\/u><\/a>.<\/p>\n\n\n\n<p>CAD\uff08\u7535\u8377\u6c14\u6eb6\u80f6\u68c0\u6d4b\u5668\uff09\u5177\u6709\u56fa\u6709\u7684\u52a8\u6001\u8303\u56f4<a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2010.01.007\"><u>\u9ad8\u8fbe\u56db\u4e2a\u6570\u91cf\u7ea7<\/u><\/a>\uff0c\u56e0\u6b64\u60a8\u53ef\u4ee5\u8f7b\u677e\u6d4b\u91cf\u540c\u4e00\u6837\u54c1\u4e2d\u4e0d\u540c\u6d53\u5ea6\u8303\u56f4\u7684\u5206\u6790\u7269\uff0c\u65e0\u9700\u5728\u4e0d\u540c\u589e\u76ca\u8303\u56f4\u4e0b\u91cd\u65b0\u5206\u6790\u6837\u54c1\u3002<\/p>\n\n\n\n<p>ELSD\uff08\u84b8\u53d1\u5149\u6563\u5c04\u68c0\u6d4b\u5668\uff09\u5219\u5927\u4e0d\u76f8\u540c\uff0c\u56e0\u4e3a\u7528\u4e8e\u6d4b\u91cf\u5149\u6563\u5c04\u7684\u5149\u7535\u500d\u589e\u7ba1\u6216\u5149\u7535\u4e8c\u6781\u7ba1\u7684\u52a8\u6001\u8303\u56f4\u76f8\u5bf9\u8f83\u5c0f\uff0c\u901a\u5e38\u53ea\u6709\u4e24\u4e2a\u6570\u91cf\u7ea7\u3002\u4e3a\u6b64\u4f1a\u91c7\u7528\u5404\u79cd\u5904\u7406\u6280\u672f\u6765\u5c1d\u8bd5\u6269\u5c55\u5176\u52a8\u6001\u8303\u56f4\uff0c\u800cCAD\u5219\u65e0\u9700\u8fd9\u4e9b\u63aa\u65bd\u3002<\/p>\n\n\n\n<p><strong>3. CAD\u54cd\u5e94\u5728\u5927\u7ea6\u4e24\u4e2a\u6570\u91cf\u7ea7\u5185\u8db3\u591f\u7ebf\u6027\uff0c\u56e0\u6b64\u8bb8\u591a\u65b9\u6cd5\u53ef\u4ee5\u4f7f\u7528\u7ebf\u6027\u6821\u51c6\u6a21\u578b<\/strong>&nbsp;<\/p>\n\n\n\n<p>CAD\u54cd\u5e94\u5728<a href=\"https:\/\/doi.org\/10.1002\/chir.20331\"><u>\u4e24\u4e2a\u6570\u91cf\u7ea7\u5185\u5448\u7ebf\u6027\u5173\u7cfb<\/u><\/a>\uff0c\u5e76\u4e14\u5177\u6709\u56db\u4e2a\u6570\u91cf\u7ea7\u7684\u52a8\u6001\u8303\u56f4\u3002\u800cELSD\u54cd\u5e94\u901a\u5e38\u53ea\u5728\u4e00\u4e2a\u6570\u91cf\u7ea7\u5185\u5448\u7ebf\u6027\uff0c\u52a8\u6001\u8303\u56f4\u4e3a\u4e24\u4e2a\u6570\u91cf\u7ea7\u3002\u56e0\u6b64\uff0c\u5927\u591a\u6570\u5206\u6790\u9700\u8981\u5728\u8fdb\u884c\u7ebf\u6027\u6821\u51c6\u524d\u8fdb\u884c\u5bf9\u6570\u8f6c\u6362\uff0c\u8fd9\u589e\u52a0\u4e86\u4e0d\u5fc5\u8981\u7684\u590d\u6742\u6027\uff0c\u5c24\u5176\u662f\u5728\u65b9\u6cd5\u9a8c\u8bc1\u548c\u53d7\u76d1\u7ba1\u5b9e\u9a8c\u5ba4\u4f7f\u7528\u65f6\u3002<\/p>\n\n\n\n<p>\u6b64\u5916\uff0c\u4f7f\u7528CAD\u65f6\uff0c\u60a8\u53ef\u4ee5\u5229\u7528\u4e00\u79cd\u72ec\u7279\u7684\u6570\u636e\u91c7\u96c6\u53c2\u6570\u53eb\u505a<a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/CMD\/Technical-Notes\/tn-73299-lc-cad-calibration-tn73299-en.pdf\"><u>\u5e42\u51fd\u6570\u503c<\/u><\/a>\uff08PFV\uff09\u8bbe\u7f6e\u7528\u4e8e\u4f18\u5316\u5728\u7ed9\u5b9a\u65b9\u6cd5\u548c\u5b9a\u91cf\u8303\u56f4\u5185\u54cd\u5e94\u8db3\u591f\u7ebf\u6027\u7684\u533a\u95f4\u3002<\/p>\n\n\n\n<p>\u7531\u4e8e\u975e\u7ebf\u6027\u54cd\u5e94\u4e5f\u4f1a\u5f71\u54cd\u5cf0\u5f62\u548c\u4fe1\u566a\u6bd4\uff0c\u4f18\u5316PFV\u8fd8\u53ef\u4ee5\u66f4\u51c6\u786e\u4e14\u7b80\u5316\u5730\u8ba1\u7b97\u6d4b\u5f97\u7684\u8272\u8c31\u5206\u8fa8\u7387\u548c\u68c0\u6d4b\u9650\u3002<\/p>\n\n\n\n<p><strong><strong>4. CAD\u54cd\u5e94\u5747\u4e00\u4e14\u4e0d\u53d7\u5316\u5b66\u7ed3\u6784\u5f71\u54cd\uff0c\u8fd9\u4e3a\u65e0\u6807\u51c6\u5b9a\u91cf\u63d0\u4f9b\u4e86\u652f\u6301<\/strong><\/strong><\/p>\n\n\n\n<p>\u54cd\u5e94\u5747\u4e00\u6027\uff08\u4e00\u81f4\u6027\uff09\u5728\u5bf9\u5206\u6790\u7269\u8fdb\u884c\u5b9a\u91cf\u65f6\u975e\u5e38\u91cd\u8981\uff0c\u5c24\u5176\u662f\u5f53<a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2020.460911\"><u>\u7f3a\u4e4f\u5355\u72ec\u6821\u51c6\u6807\u51c6\u54c1\u65f6<\/u><\/a>\uff0c\u5982\u836f\u7269\u7814\u53d1\u3001\u6742\u8d28\u5206\u6790\u4ee5\u53ca\u5316\u5408\u7269\u5e93\u7ba1\u7406\u3002<\/p>\n\n\n\n<p>CAD\u6bd4ELSD\u5728\u65e0\u6807\u51c6\u5b9a\u91cf\u65b9\u9762\u66f4\u51c6\u786e\uff0c\u539f\u56e0\u6709\u4e24\u70b9\uff1a\u5176\u4e00\u662f\u8de8\u591a\u79cd\u5316\u5b66\u7ed3\u6784\u7684\u5206\u6790\u7269\u54cd\u5e94\u76f8\u4f3c\uff0c\u5176\u4e8c\u662f\u53ef\u4ee5\u5e94\u7528\u53cd\u68af\u5ea6\u6765\u8865\u507f\u8fc7\u7a0b\u4e2d\u54cd\u5e94\u53d8\u5316\u3002<a href=\"https:\/\/doi.org\/10.1080\/10826071003608520\"><u>\u6807\u51c6\u81ea\u7531\u91cf\u5316<\/u><\/a>\u6709\u4e24\u4e2a\u91cd\u8981\u539f\u56e0\uff1a\u4e00\u662f\u56e0\u4e3a\u5728\u5404\u79cd\u5316\u5b66\u7ed3\u6784\u4e2d\uff0c\u4e0d\u540c\u5206\u6790\u7269\u7684\u54cd\u5e94\u76f8\u4f3c\uff1b\u4e8c\u662f\u4f60\u53ef\u4ee5\u5e94\u7528\u53cd\u5411\u68af\u5ea6\u6765\u8865\u507f\u5206\u6790\u8fc7\u7a0b\u4e2d\u54cd\u5e94\u7684\u53d8\u5316\u3002<a href=\"https:\/\/doi.org\/10.1080\/10826070802603187\"><u>\u68af\u5ea6\u6d17\u8131<\/u><\/a>.<\/p>\n\n\n\n<p>\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u5206\u6790\u7269\u7684\u7406\u5316\u6027\u8d28\u5bf9ELSD\u54cd\u5e94\u7684\u5f71\u54cd\u53ef\u80fd\u6bd4CAD\u66f4\u5927\u3002\u4f8b\u5982\uff0c\u5206\u6790\u7269\u7684\u6298\u5c04\u7387\u3001\u5149\u5438\u6536\u548c\u8367\u5149\u7b49\u7279\u6027\u90fd\u88ab\u62a5\u9053\u4f1a\u5f71\u54cdELSD\u54cd\u5e94\u3002<\/p>\n\n\n\n<p>\u6b64\u5916\uff0c\u5728\u4f7f\u7528ELSD\u65f6\uff0c\u4f60\u9009\u62e9\u4f5c\u4e3a\u66ff\u4ee3\u6807\u51c6\u7684\u5cf0\u53ef\u80fd\u4e0d\u4f1a\u50cf\u4f60\u5173\u6ce8\u7684\u76ee\u6807\u5cf0\u90a3\u6837\u8868\u73b0\u4e00\u81f4\u3002<\/p>\n\n\n\n<p><strong><strong>5. ELSD\u54cd\u5e94\u66f2\u7ebf\u590d\u6742\u7684\u5f62\u72b6\u5e38\u5e38\u5bfc\u81f4\u66f4\u591a\u9650\u5236\u548c\u66f4\u5927\u7684\u4e0d\u51c6\u786e\u6027<\/strong><\/strong><\/p>\n\n\n\n<p>CAD\u548cELSD\u7684\u54cd\u5e94\u66f2\u7ebf\u5b8c\u5168\u76f8\u53cd\uff08\u89c1\u56fe1\uff09\u3002\u5728\u6574\u4e2a\u8303\u56f4\u5185\uff0cELSD\u54cd\u5e94\u66f2\u7ebf\u5728\u5f2f\u66f2\u7a0b\u5ea6\u548c\u65b9\u5411\u4e0a\u90fd\u663e\u793a\u51fa\u5267\u70c8\u53d8\u5316\u3002\u8fd9\u4e9b\u6025\u5267\u53d8\u5316\u901a\u5e38\u4e0e\u4e0d\u7cbe\u786e\u548c\u4e0d\u51c6\u786e\u76f8\u5173\uff0c\u56e0\u4e3a\u6563\u5c04\u5149\u5f3a\u5ea6\u968f\u7740\u7c92\u5f84\u5448\u6307\u6570\u53d8\u5316\uff0c\u4ece\u800c\u4ea7\u751f\u590d\u6742\u7684S\u578b\u54cd\u5e94\u66f2\u7ebf\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/admin.acceleratingscience.com\/analyteguru\/wp-content\/uploads\/sites\/25\/2024\/02\/CAD-vs-ELSD-response-curves.png\" alt=\"\" class=\"wp-image-17092\" style=\"width:781px;height:auto\" \/><figcaption class=\"wp-element-caption\">\u56fe1. ELSD\uff08\u5de6\uff09\u548cCAD\uff08\u53f3\uff09\u7684\u54cd\u5e94\u66f2\u7ebf\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u8fd9\u79cd\u590d\u6742\u884c\u4e3a\u5f88\u5927\u7a0b\u5ea6\u4e0a\u53ef\u4ee5\u901a\u8fc7\u8003\u8651\u8f83\u5c0f\u6c14\u6eb6\u80f6\u9897\u7c92\uff08\u5c0f\u4e8e\u7ea650\u7eb3\u7c73\uff09\uff0c\u5373\u5728\u4f4e\u5206\u6790\u7269\u6d53\u5ea6\u53ca\u4efb\u4f55\u8272\u8c31\u5cf0\u8fb9\u7f18\u5360\u4e3b\u5bfc\u5730\u4f4d\u7684\u9897\u7c92\u6240\u4ea7\u751f\u7684\u9884\u671f\u4fe1\u53f7\u6765\u89e3\u91ca\u3002<\/p>\n\n\n\n<p>\u5bf9\u4e8e\u8fd9\u4e2a\u7c92\u5f84\u8303\u56f4\uff0c\u7406\u8bba\u4e0a\u6d53\u5ea6\u4e0b\u964d\u5bfc\u81f4\u9897\u7c92\u76f4\u5f84\u51cf\u5c11\u4e00\u534a\uff0c\u5e94\u4f1a\u5f15\u8d77\u6563\u5c04\u5149\u5f3a\u5ea6\u7ea664\u500d\u7684\u4e0b\u964d\uff0c\u8fd9\u4e0e10\u6210\u6b63\u6bd4\u30026\u5bf9\u4e8e<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/book\/10.1002\/9781119390725\"><u>\u745e\u5229\u6563\u5c04<\/u><\/a>\u8fd9\u79cd\u7075\u654f\u5ea6\u7684\u635f\u5931\u901a\u5e38\u8868\u73b0\u4e3aELSD\u4fe1\u53f7\u7684\u7a81\u7136\u6d88\u5931\u6216\u6025\u5267\u4e0b\u964d\u3002<\/p>\n\n\n\n<p>\u5bf9\u4e8eCAD\uff0c\u76f8\u540c\u7684\u7c92\u5f84\u51cf\u5c0f\u53ea\u4f1a\u5bfc\u81f4\u6bcf\u4e2a\u9897\u7c92\u7535\u8377\u91cf\u7ea6\u51cf\u5c11\u4e24\u500d\uff0c\u4ece\u800c\u4ea7\u751f\u66f4\u7b80\u5355\u4e14\u66f4\u63a5\u8fd1\u7ebf\u6027\u7684\u5173\u7cfb\uff0c\u8bb8\u591a\u76f4\u63a5\u5bf9\u6bd4\u7814\u7a76\u8868\u660eCAD\u5728\u7cbe\u5bc6\u5ea6\u548c\u51c6\u786e\u6027\u65b9\u9762\u4f18\u4e8eELSD\u3002<\/p>\n\n\n\n<p><strong><strong>6. ELSD\u4e0d\u662f\u7ebf\u6027\u68c0\u6d4b\u5668\uff0c\u901a\u8fc7\u9ad8\u6d53\u5ea6\u6807\u51c6\u54c1\u63a8\u7b97\u7684\u201c\u4f30\u7b97\u201dLOD\u548cLOQ\u6beb\u65e0\u610f\u4e49<\/strong><\/strong><\/p>\n\n\n\n<p>\u901a\u5e38\u505a\u6cd5\u662f\u901a\u8fc7\u9ad8\u6d53\u5ea6\u6807\u51c6\u54c1\u4fe1\u566a\u6bd4\u5916\u63a8\u6765\u4f30\u7b97\u7ebf\u6027\u68c0\u6d4b\u5668\u7684\u68c0\u51fa\u9650\uff08LOD\uff09\u6216\u5b9a\u91cf\u9650\uff08LOQ\uff09\uff0c\u4f46\u7528\u8fd9\u79cd\u65b9\u6cd5\u63a8\u7b97ELSD\u7684\u7ed3\u679c\u5f80\u5f80\u6781\u5177\u8bef\u5bfc\u6027\u3002<\/p>\n\n\n\n<p>\u539f\u56e0\u5728\u4e8eELSD\u5bf9\u8f83\u5c0f\u9897\u7c92\u54cd\u5e94\u51fa\u73b0\u663e\u8457\u201c\u9aa4\u964d\u201d\uff0c\u56e0\u6b64\u5e94\u901a\u8fc7\u5b9e\u9645\u5206\u6790\u6765\u786e\u5b9aLOD\u548cLOQ\u3002<a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2007.09.008\"><u>\u9010\u6e10\u964d\u4f4e\u5206\u6790\u7269\u6d53\u5ea6\u8fdb\u884c\u5206\u6790<\/u><\/a>.<\/p>\n\n\n\n<p>\u7ebf\u6027\u8bc4\u4f30\u5e94\u5305\u62ec\u5bf9\u51c6\u786e\u5ea6\u6216\u56de\u6536\u7387\u7684\u4ed4\u7ec6\u68c0\u67e5\uff0c\u5c24\u5176\u662f\u5728\u4f4e\u6d53\u5ea6\u65f6\u3002<\/p>\n\n\n\n<p><strong><strong>\u63a2\u7d22\u60a8\u7684\u5b9e\u9a8c\u5ba4\u5982\u4f55\u53d7\u76ca\u4e8e\u4f7f\u7528\u5e26\u7535\u6c14\u6eb6\u80f6\u68c0\u6d4b\u6280\u672f<\/strong><\/strong><\/p>\n\n\n\n<p>\u5982\u60a8\u6240\u89c1\uff0cCAD\u5728\u5206\u6790\u4e0a\u76f8\u6bd4ELSD\u5177\u6709\u8bf8\u591a\u4f18\u52bf\uff0c\u8fd9\u76f4\u63a5\u6e90\u81ea\u7535\u6c14\u6eb6\u80f6\u68c0\u6d4b\u4e0e\u5149\u6563\u5c04\u68c0\u6d4b\u5404\u81ea\u7684\u7279\u70b9\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/admin.acceleratingscience.com\/analyteguru\/wp-content\/uploads\/sites\/25\/2024\/02\/CAD_ELSD_HPLC_detector_comparison.png\" alt=\"\" class=\"wp-image-17091\" \/><\/figure>\n\n\n\n<p>\u4e86\u89e3\u5982\u4f55\u52a0\u901f\u60a8\u7684\u5de5\u4f5c<a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/chromatography\/chromatography-learning-center\/liquid-chromatography-information\/hplc-system-components\/how-hplc-detectors-work\/charged-aerosol-detection\/charged-aerosol-detector-cad-literature-references.html?filter=Application%20area%7Cpharmaceuticalandbiopharmaceutical&amp;\"><u>\u836f\u7269\u53d1\u73b0<\/u><\/a>\u63d0\u5347\u914d\u65b9\u7a33\u5b9a\u6027<a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/chromatography\/chromatography-learning-center\/liquid-chromatography-information\/hplc-system-components\/how-hplc-detectors-work\/charged-aerosol-detection.html\"><u>HPLC-CAD \u6280\u672f<\/u><\/a>\u7acb\u5373\u4f53\u9a8c\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-\u6587\u732e\u53c2\u8003\"><strong><strong>\u6587\u732e\u53c2\u8003<\/strong><\/strong><\/h3>\n\n\n\n<ol class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.1080\/10826070802603187\" target=\"_blank\" rel=\"noreferrer noopener\">Sensitive Determination of Saponins in Radix et Rhizoma Notoginseng by Charged Aerosol Detector Coupled with HPLC<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2010.04.047\" target=\"_blank\" rel=\"noreferrer noopener\">Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2007.09.008\" target=\"_blank\" rel=\"noreferrer noopener\">Comparison of universal detectors for high-temperature micro liquid chromatography<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2009.11.036\" target=\"_blank\" rel=\"noreferrer noopener\">Control of impurities in L\u2010aspartic acid and L\u2010alanine by high\u2010performance liquid chromatography coupled with a corona charged aerosol detector<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1002\/jssc.201000141\" target=\"_blank\" rel=\"noreferrer noopener\">Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1002\/9781119390725.ch11\" target=\"_blank\" rel=\"noreferrer noopener\">Impurity Control in Topiramate with High Performance Liquid Chromatography<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.talanta.2011.04.012\" target=\"_blank\" rel=\"noreferrer noopener\">Comparison of two aerosol\u2010based detectors for the analysis of gabapentin in pharmaceutical formulations by hydrophilic interaction chromatography<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2009.05.043\" target=\"_blank\" rel=\"noreferrer noopener\">Size exclusion chromatography with Corona charged aerosol detector for the analysis of polyethylene glycol polymer<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.talanta.2016.01.027\" target=\"_blank\" rel=\"noreferrer noopener\">A non-derivative method for the quantitative analysis of isosteroidal alkaloids from&nbsp;Fritillaria&nbsp;by high performance liquid chromatography combined with charged aerosol detection<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.researchgate.net\/profile\/Baiwei-Lin\/publication\/228510094_Evaluation_of_Charged_Aerosol_Detection_CAD_as_a_Complementary_Technique_for_High-Throughput_LC-MS-UV-ELSD_Analysis_of_Drug_Discovery_Screening\/links\/560d5d2208aeed9d13751f9e\/Evaluation-of-Charged-Aerosol-Detection-CAD-as-a-Complementary-Technique-for-High-Throughput-LC-MS-UV-ELSD-Analysis-of-Drug-Discovery-Screening.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Evaluation of charged aerosol detection (CAD) as a complementary technique for high\u2010throughput LC\u2010MS\u2010UV\u2010ELSD analysis of drug discovery screening libraries<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1080\/10826071003608520\" target=\"_blank\" rel=\"noreferrer noopener\">Quantitative study of the stratum corneum lipid classes by normal phase liquid chromatography: comparison between two universal detectors<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.jpba.2008.10.027\" target=\"_blank\" rel=\"noreferrer noopener\">Aerosol based detectors for the investigation of phospholipid hydrolysis in a pharmaceutical suspension formulation<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/s00216-007-1774-1\" target=\"_blank\" rel=\"noreferrer noopener\">Polyketide analysis using mass spectrometry, evaporative light scattering, and charged aerosol detector systems<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2008.07.080\" target=\"_blank\" rel=\"noreferrer noopener\">Comparison between charged aerosol detection and light scattering detection for the analysis of Leishmania membrane phospholipids<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2020.460911\" target=\"_blank\" rel=\"noreferrer noopener\">Recent applications of the Charged Aerosol Detector for liquid chromatography in drug quality control<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.jpba.2009.10.019\" target=\"_blank\" rel=\"noreferrer noopener\">Comparison of ultraviolet detection, evaporative light scattering detection and charged aerosol detection methods for liquid\u2010chromatographic determination of anti\u2010diabetic drugs<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2008.04.012\" target=\"_blank\" rel=\"noreferrer noopener\">Quantitative comparison of a corona\u2010charged aerosol detector and an evaporative light\u2010 scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2010.01.007\" target=\"_blank\" rel=\"noreferrer noopener\">Review of operating principle and applications of the charged aerosol detector<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2007.10.111\" target=\"_blank\" rel=\"noreferrer noopener\">Performance evaluation of evaporative light scattering detection and charged aerosol detection in reversed phase liquid chromatography<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1365\/s10337-009-1192-y\" target=\"_blank\" rel=\"noreferrer noopener\">Performance evaluation of charged aerosol and evaporative light scattering detection for the determination of ginsenosides by LC<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1002\/chir.20331\" target=\"_blank\" rel=\"noreferrer noopener\">HPLC determinations of enantiomeric ratios<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ingentaconnect.com\/content\/jpa\/cjpa\/2014\/00000034\/00000003\/art00030#expand\/collapse\" target=\"_blank\" rel=\"noreferrer noopener\">Comparison of ELSD and CAD methods for determination of phosphatidylcholine content in polyene phosphatidycholine injection<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.lctsbible.com\/tsb-pdf\/22022004.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Kiser, M. M.; Dolan, J. W. Selecting the best curve fit. LC GC North America 2004, 22(2), 112\u2013117.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1570023202002441\" target=\"_blank\" rel=\"noreferrer noopener\">Almeida, A. M. d., et al. Linear regression for calibration lines revisited: weighting schemes for bioanalytical methods. Journal of Chromatography B 2002, 774(2), 215\u2013222.<\/a><\/li>\n<\/ol>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5728 HPLC\/UHPLC \u5206\u6790\u4e2d\uff0c\u6700\u5e38\u7528\u7684\u68c0\u6d4b\u5668\u662f UV-Vis\uff08\u7d2b\u5916-\u53ef\u89c1\uff09\u68c0\u6d4b\u5668\u3002\u4f46\u5982\u679c\u4f60\u7684\u5206\u6790\u7269\u6ca1\u6709\u53d1\u8272<\/p>\n","protected":false},"author":1852,"featured_media":752,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[49],"tags":[80,81,74],"division":[50],"class_list":{"0":"post-751","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-49","8":"tag-cad","9":"tag-elsd","10":"tag-hplc","11":"division-cmd","12":"entry"},"_selected_authors":[767],"_selected_reviewers":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f - \u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2<\/title>\n<meta name=\"description\" content=\"\u5e26\u7535\u6c14\u6eb6\u80f6(CAD)\u68c0\u6d4b\u6cd5\u5728\u672c\u8d28\u4e0a\u548c\u6301\u7eed\u6027\u65b9\u9762\u90fd\u6bd4\u5149\u6563\u5c04\u6cd5(ELSD)\u66f4\u4e3a\u7075\u654f\uff0c\u5e76\u5bf9\u6027\u80fd\u4ea7\u751f\u4e86\u91cd\u5927\u5f71\u54cd\u3002\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f\" \/>\n<meta property=\"og:description\" content=\"\u5e26\u7535\u6c14\u6eb6\u80f6(CAD)\u68c0\u6d4b\u6cd5\u5728\u672c\u8d28\u4e0a\u548c\u6301\u7eed\u6027\u65b9\u9762\u90fd\u6bd4\u5149\u6563\u5c04\u6cd5(ELSD)\u66f4\u4e3a\u7075\u654f\uff0c\u5e76\u5bf9\u6027\u80fd\u4ea7\u751f\u4e86\u91cd\u5927\u5f71\u54cd\u3002\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/\" \/>\n<meta property=\"og:site_name\" content=\"\u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2026-03-09T09:05:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-13T02:50:14+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/03\/cad-VS-elsd.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"857\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Calvin Ye\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Calvin Ye\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 \u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/\"},\"author\":{\"name\":\"Calvin Ye\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/#\\\/schema\\\/person\\\/8e7a640047c10da2b7107498ddb447d6\"},\"headline\":\"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f\",\"datePublished\":\"2026-03-09T09:05:05+00:00\",\"dateModified\":\"2026-05-13T02:50:14+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/\"},\"wordCount\":470,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/wp-content\\\/uploads\\\/sites\\\/28\\\/2026\\\/03\\\/cad-VS-elsd.jpg\",\"keywords\":[\"CAD\",\"ELSD\",\"HPLC\"],\"articleSection\":[\"\u8272\u8c31\u4e0e\u8d28\u8c31\"],\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/\",\"name\":\"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f - \u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/wp-content\\\/uploads\\\/sites\\\/28\\\/2026\\\/03\\\/cad-VS-elsd.jpg\",\"datePublished\":\"2026-03-09T09:05:05+00:00\",\"dateModified\":\"2026-05-13T02:50:14+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/#\\\/schema\\\/person\\\/8e7a640047c10da2b7107498ddb447d6\"},\"description\":\"\u5e26\u7535\u6c14\u6eb6\u80f6(CAD)\u68c0\u6d4b\u6cd5\u5728\u672c\u8d28\u4e0a\u548c\u6301\u7eed\u6027\u65b9\u9762\u90fd\u6bd4\u5149\u6563\u5c04\u6cd5(ELSD)\u66f4\u4e3a\u7075\u654f\uff0c\u5e76\u5bf9\u6027\u80fd\u4ea7\u751f\u4e86\u91cd\u5927\u5f71\u54cd\u3002\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#breadcrumb\"},\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#primaryimage\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/wp-content\\\/uploads\\\/sites\\\/28\\\/2026\\\/03\\\/cad-VS-elsd.jpg\",\"contentUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/wp-content\\\/uploads\\\/sites\\\/28\\\/2026\\\/03\\\/cad-VS-elsd.jpg\",\"width\":1200,\"height\":857},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.thermofisher.cn\\\/blog\\\/accelerating-science-in-china\\\/cad-vs-elsd-which-hplc-detector-is-your-better-option\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/#website\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/\",\"name\":\"\u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/accelerating-science-in-china\\\/#\\\/schema\\\/person\\\/8e7a640047c10da2b7107498ddb447d6\",\"name\":\"Calvin Ye\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/bbe4236bccb5fcea6db0797643cf62d5613a642669442510a90ed606595e6a27?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/bbe4236bccb5fcea6db0797643cf62d5613a642669442510a90ed606595e6a27?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/bbe4236bccb5fcea6db0797643cf62d5613a642669442510a90ed606595e6a27?s=96&d=mm&r=g\",\"caption\":\"Calvin Ye\"},\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/author\\\/calvin-yethermofisher-com\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f - \u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2","description":"\u5e26\u7535\u6c14\u6eb6\u80f6(CAD)\u68c0\u6d4b\u6cd5\u5728\u672c\u8d28\u4e0a\u548c\u6301\u7eed\u6027\u65b9\u9762\u90fd\u6bd4\u5149\u6563\u5c04\u6cd5(ELSD)\u66f4\u4e3a\u7075\u654f\uff0c\u5e76\u5bf9\u6027\u80fd\u4ea7\u751f\u4e86\u91cd\u5927\u5f71\u54cd\u3002","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/","og_locale":"zh_CN","og_type":"article","og_title":"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f","og_description":"\u5e26\u7535\u6c14\u6eb6\u80f6(CAD)\u68c0\u6d4b\u6cd5\u5728\u672c\u8d28\u4e0a\u548c\u6301\u7eed\u6027\u65b9\u9762\u90fd\u6bd4\u5149\u6563\u5c04\u6cd5(ELSD)\u66f4\u4e3a\u7075\u654f\uff0c\u5e76\u5bf9\u6027\u80fd\u4ea7\u751f\u4e86\u91cd\u5927\u5f71\u54cd\u3002","og_url":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/","og_site_name":"\u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2","article_publisher":"https:\/\/www.facebook.com\/thermofisher","article_published_time":"2026-03-09T09:05:05+00:00","article_modified_time":"2026-05-13T02:50:14+00:00","og_image":[{"width":1200,"height":857,"url":"http:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/03\/cad-VS-elsd.jpg","type":"image\/jpeg"}],"author":"Calvin Ye","twitter_card":"summary_large_image","twitter_creator":"@thermofisher","twitter_site":"@thermofisher","twitter_misc":{"Written by":"Calvin Ye","Est. reading time":"4 \u5206"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#article","isPartOf":{"@id":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/"},"author":{"name":"Calvin Ye","@id":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/#\/schema\/person\/8e7a640047c10da2b7107498ddb447d6"},"headline":"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f","datePublished":"2026-03-09T09:05:05+00:00","dateModified":"2026-05-13T02:50:14+00:00","mainEntityOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/"},"wordCount":470,"commentCount":0,"image":{"@id":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/03\/cad-VS-elsd.jpg","keywords":["CAD","ELSD","HPLC"],"articleSection":["\u8272\u8c31\u4e0e\u8d28\u8c31"],"inLanguage":"zh-Hans","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.thermofisher.com\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/","url":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/","name":"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f - \u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2","isPartOf":{"@id":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#primaryimage"},"image":{"@id":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/03\/cad-VS-elsd.jpg","datePublished":"2026-03-09T09:05:05+00:00","dateModified":"2026-05-13T02:50:14+00:00","author":{"@id":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/#\/schema\/person\/8e7a640047c10da2b7107498ddb447d6"},"description":"\u5e26\u7535\u6c14\u6eb6\u80f6(CAD)\u68c0\u6d4b\u6cd5\u5728\u672c\u8d28\u4e0a\u548c\u6301\u7eed\u6027\u65b9\u9762\u90fd\u6bd4\u5149\u6563\u5c04\u6cd5(ELSD)\u66f4\u4e3a\u7075\u654f\uff0c\u5e76\u5bf9\u6027\u80fd\u4ea7\u751f\u4e86\u91cd\u5927\u5f71\u54cd\u3002","breadcrumb":{"@id":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#breadcrumb"},"inLanguage":"zh-Hans","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/"]}]},{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#primaryimage","url":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/03\/cad-VS-elsd.jpg","contentUrl":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/03\/cad-VS-elsd.jpg","width":1200,"height":857},{"@type":"BreadcrumbList","@id":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/cad-vs-elsd-which-hplc-detector-is-your-better-option\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/"},{"@type":"ListItem","position":2,"name":"CAD \u4e0e ELSD\uff1a\u54ea\u79cd HPLC \u68c0\u6d4b\u5668\u66f4\u9002\u5408\u60a8\uff1f"}]},{"@type":"WebSite","@id":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/#website","url":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/","name":"\u8d5b\u9ed8\u98de\u4e2d\u6587\u535a\u5ba2","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-Hans"},{"@type":"Person","@id":"https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/#\/schema\/person\/8e7a640047c10da2b7107498ddb447d6","name":"Calvin Ye","image":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/secure.gravatar.com\/avatar\/bbe4236bccb5fcea6db0797643cf62d5613a642669442510a90ed606595e6a27?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/bbe4236bccb5fcea6db0797643cf62d5613a642669442510a90ed606595e6a27?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/bbe4236bccb5fcea6db0797643cf62d5613a642669442510a90ed606595e6a27?s=96&d=mm&r=g","caption":"Calvin Ye"},"url":"https:\/\/admin.acceleratingscience.com\/author\/calvin-yethermofisher-com\/"}]}},"taxonomy_info":{"category":[{"value":49,"label":"\u8272\u8c31\u4e0e\u8d28\u8c31"}],"post_tag":[{"value":80,"label":"CAD"},{"value":81,"label":"ELSD"},{"value":74,"label":"HPLC"}],"division":[{"value":50,"label":"CMD"}]},"featured_image_src_large":["https:\/\/admin.acceleratingscience.com\/accelerating-science-in-china\/wp-content\/uploads\/sites\/28\/2026\/03\/cad-VS-elsd-1024x731.jpg",760,543,true],"author_info":{"display_name":"Calvin Ye","author_link":"https:\/\/admin.acceleratingscience.com\/author\/calvin-yethermofisher-com\/"},"comment_info":0,"category_info":[{"term_id":49,"name":"\u8272\u8c31\u4e0e\u8d28\u8c31","slug":"%e8%89%b2%e8%b0%b1%e4%b8%8e%e8%b4%a8%e8%b0%b1","term_group":0,"term_taxonomy_id":49,"taxonomy":"category","description":"","parent":0,"count":38,"filter":"raw","meta":[],"cat_ID":49,"category_count":38,"category_description":"","cat_name":"\u8272\u8c31\u4e0e\u8d28\u8c31","category_nicename":"%e8%89%b2%e8%b0%b1%e4%b8%8e%e8%b4%a8%e8%b0%b1","category_parent":0}],"tag_info":[{"term_id":80,"name":"CAD","slug":"cad","term_group":0,"term_taxonomy_id":80,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","meta":[]},{"term_id":81,"name":"ELSD","slug":"elsd","term_group":0,"term_taxonomy_id":81,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","meta":[]},{"term_id":74,"name":"HPLC","slug":"hplc","term_group":0,"term_taxonomy_id":74,"taxonomy":"post_tag","description":"","parent":0,"count":8,"filter":"raw","meta":[]}],"_links":{"self":[{"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/posts\/751","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/users\/1852"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/comments?post=751"}],"version-history":[{"count":0,"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/posts\/751\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/media\/752"}],"wp:attachment":[{"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/media?parent=751"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/categories?post=751"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/tags?post=751"},{"taxonomy":"division","embeddable":true,"href":"https:\/\/www.thermofisher.cn\/blog\/accelerating-science-in-china\/wp-json\/wp\/v2\/division?post=751"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}