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5HT3D R/5HT3E R Polyclonal Antibody
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产品信息
OSS00194W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from c-terminal region of human 5HT3D receptor (Serotonin receptor 3D) conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in 5HT3E.
Specificity of this antibody: 5HT3D, 5HT3E receptors.
靶标信息
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Subcellular Location: Cell membrane; Multi-pass membrane protein. Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. Tissue Specificity: 5HT3D: Expressed in liver, as well as fetal and adult colon and kidney. 5HT3E: Expressed in adult colon and intestine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5-HT-1E; 5-HT3-D; 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled; 5-hydroxytryptamine (serotonin) receptor 3 family member D; 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic; 5-hydroxytryptamine receptor 1E; 5-hydroxytryptamine receptor 3 subunit D; 5-hydroxytryptamine receptor 3D; S31; serotonin 5-HT-3D receptor; Serotonin receptor 1E; Serotonin receptor 3D
基因别名: 5-HT1E; 5HT3D; HTR1E; HTR3D
UniProt ID: (Human) P28566, (Human) Q70Z44
Entrez Gene ID: (Human) 3354, (Human) 200909
G-protein coupled receptor activity
G-protein coupled serotonin receptor activity
protein binding
serotonin binding
acetylcholine-activated cation-selective channel activity
serotonin-activated cation-selective channel activity
acetylcholine receptor activity
acetylcholine binding
G-protein coupled receptor
ligand-gated ion channel
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
serotonin receptor signaling pathway
chemical synaptic transmission
negative regulation of cAMP metabolic process
synaptic transmission, cholinergic
ion transmembrane transport
cation transmembrane transport
