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Proteintech
BCAR3 Polyclonal Antibody
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产品信息
13628-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BCAR3 Fusion Protein Ag4546 (475-825 aa encoded by BC039895)
偶联物
形式
Liquid
浓度
0.14 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: YLILDDDDR ERPWEPAAAQ MEKGQWDKGE FVTPLLETVS SFRPNEFESK FLPPENKPLE TAMLKRAKEL FTNNDPKVIA QHVLSMDCRV ARILGVSEEM RRNMGVSSGL ELITLPHGHQ LRLDIIERHN TMAIGIAVDI LGCTGTLEDR AATLSKIIQV AVELKDSMGD LYSFSALMKA LEMPQITRLE KTWTALRHQY TQTAILYEKQ LKPFSKLLHE GRESTCVPPN NVSVPLLMPL VTLMERQAVT FEGTDMWEKN DQSCEIMLNH LATARFMAEA ADSYRMNAER ILAGFQPDEE MNEICKTEFQ MRLLWGSKGA QVNQTERYEK FNQILTALSR KLEPPPVKQA EL (475-825 aa encoded by BC039895)
靶标信息
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCAR3 adapter protein, NSP family member; Breast cancer anti-estrogen resistance protein 3; Breast cancer anti-estrogen resistance protein 3 homolog; breast cancer antiestrogen resistance 3 protein; dJ1033H22.2 (breast cancer anti-estrogen resistance 3); KIAA0554; Novel SH2-containing protein 2; OTTHUMP00000011961; p130Cas-binding protein AND-34; SH2 domain-containing protein 3B
基因别名: AI131758; AND-34; And34; BCAR3; NSP2; SH2D3B; UNQ271/PRO308
UniProt ID: (Human) O75815, (Mouse) Q9QZK2, (Rat) D3ZAZ5
Entrez Gene ID: (Human) 8412, (Mouse) 29815, (Rat) 310838
