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Invitrogen
C6orf57 Polyclonal Antibody
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C6orf57 Antibody (PA5-73014) in WB
Western blot analysis of C6orf57 in mouse embryo body tissue lysates. Samples were incubated with C6orf57 polyclonal antibody (Product # PA5-73014) followed by Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution. Lysates in the 1) absence and 2) presence of immunizing peptide.
产品信息
PA5-73014
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 75-129 of mouse UPF0369 protein C6orf57 homolog.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The amino acid sequence used as immunogen is 100% homologous in mouse, and 94% homologous in human, monkey, dog and rat.
靶标信息
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416). Binds to the flavoprotein subunit Sdha in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit Sdhb into the SDH catalytic dimer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: SDH assembly factor 4; Succinate dehydrogenase assembly factor 4, mitochondrial; UPF0369 protein C6orf57 homolog
基因别名: 1110058L19Rik; 1700001E18Rik; C6orf57; Sdhaf4
UniProt ID: (Mouse) Q8BTE0
Entrez Gene ID: (Mouse) 68002
