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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SRGRLNSFTQ GILPIAFSRP TSQNYCSLEQ PGQGGSTSAF EQLQRSRRRL ISQRSSLETL EDIEENAPLR RCRTLSGSPR PKN
Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 94%.
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CDK5 and ABL1 enzyme substrate 1; Ik3-1; Interactor with CDK3 1
基因别名: CABLES; CABLES1
Entrez Gene ID: (Human) 91768