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Proteintech
CBS Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
14787-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Dog,
Human,
Mouse,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CBS Fusion Protein Ag6437 (206-551 aa encoded by BC000440)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.31 mg/mL
规格
46.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VAWRLKNEI PNSHILDQYR NASNPLAHYD TTADEILQQC DGKLDMLVAS VGTGGTITGI ARKLKEKCPG CRIIGVDPEG SILAEPEELN QTEQTTYEVE GIGYDFIPTV LDRTVVDKWF KSNDEEAFTF ARMLIAQEGL LCGGSAGSTV AVAVKAAQEL QEGQRCVVIL PDSVRNYMTK FLSDRWMLQK GFLKEEDLTE KKPWWWHLRV QELGLSAPLT VLPTITCGHT IEILREKGFD QAPVVDEAGV ILGMVTLGNM LSSLLAGKVQ PSDQVGKVIY KQFKQIRLTD TLGRLSHILE MDHFALVVHE QIQYHSTGKS SQRQMVFGVV TAIDLLNFVA AQERDQK (206-551 aa encoded by BC000440 )
靶标信息
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: beta-thionase; hemoprotein H-450; methylcysteine synthase; serine sulfhydrase; unnamed protein product
基因别名: HIP4
UniProt ID: (Human) P35520, (Mouse) Q91WT9, (Rat) P32232
Entrez Gene ID: (Human) 875, (Mouse) 12411, (Rat) 24250
cystathionine beta-synthase activity
protein binding
oxygen binding
enzyme binding
heme binding
pyridoxal phosphate binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
nitrite reductase (NO-forming) activity
carbon monoxide binding
nitric oxide binding
modified amino acid binding
S-adenosyl-L-methionine binding
selenocystathionine beta-synthase activity
selenium compound metabolic process
endochondral ossification
blood vessel remodeling
L-serine metabolic process
L-serine catabolic process
superoxide metabolic process
cysteine biosynthetic process
transsulfuration
L-cysteine catabolic process
cerebellum morphogenesis
response to nutrient levels
cellular response to insulin stimulus
DNA protection
negative regulation of apoptotic process
homocysteine catabolic process
sulfur compound biosynthetic process
regulation of JNK cascade
homocysteine metabolic process
response to folic acid
maternal process involved in female pregnancy
cartilage development involved in endochondral bone morphogenesis
hydrogen sulfide biosynthetic process
cellular response to hypoxia
regulation of blood vessel diameter
negative regulation of nitric oxide-cGMP mediated signal transduction
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