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Invitrogen
CD300a Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-113473
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CMRF35-like molecule 8 protein (18-180AA)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.58 mg/mL
Amount
158 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998 [PubMed 9701027]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD300 antigen-like family member A; CD300A antigen; clm-8; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35HIRp60; immunoglobulin superfamily member 12; inhibitory receptor protein 60; IRC1a; IRC1b; IRC1c; leukocyte membrane antigen; leukocyte mono-Ig-like receptor 1; mast cell-derived paired immunoglobulin-like receptor 1; Mcipr1; myeloid-associated immunoglobulin-like receptor 1; NK inhibitory receptor; NKRL; polymeric immunoglobulin receptor 4; unnamed protein product
Gene Aliases: B230315M08Rik; CLM-8; Clm8; CMRF-35-H9; CMRF-35H; CMRF35-H; CMRF35-H9; CMRF35H; CMRF35H9; IGSF12; IRC1; IRC1/IRC2; IRC2; IRp60; LMIR1; MAIR-1; MAIR-I; MAIR-Ia; mcpir1; MMAC8; Pigr4
UniProt ID: (Human) Q9UGN4, (Mouse) Q6SJQ0
Entrez Gene ID: (Human) 11314, (Mouse) 217303
serotonin secretion by mast cell
receptor-mediated endocytosis
signal transduction
negative regulation of serotonin secretion
negative regulation of B cell proliferation
negative regulation of mast cell activation involved in immune response
negative regulation of MyD88-dependent toll-like receptor signaling pathway
intracellular signal transduction
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
regulation of innate immune response
negative regulation of fibroblast proliferation
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of eosinophil migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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