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Invitrogen
CD3g Polyclonal Antibody
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CD3g Antibody (PA5-102995) in ICC/IF
Immunofluorescent analysis of CD3/CD8 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CD3/CD8 polyclonal antibody (Product # PA5-102995) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-102995
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CD3G(Accession P09693), corresponding to amino acid residues G117-E167.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CD3G.
靶标信息
CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD3 antigen, gamma polypeptide; CD3 gamma-chain; CD3 molecule, gamma polypeptide; CD3g; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain
基因别名: CD3-GAMMA; CD3G; Ctg-3; Ctg3; IMD17; T3G
UniProt ID: (Human) P09693, (Mouse) P11942, (Rat) Q64159
Entrez Gene ID: (Human) 917, (Mouse) 12502, (Rat) 300678
establishment or maintenance of cell polarity
cell surface receptor signaling pathway
protein transport
regulation of lymphocyte apoptotic process
biological_process
protein complex assembly
T cell costimulation
Fc-gamma receptor signaling pathway involved in phagocytosis
T cell activation
regulation of immune response
T cell receptor signaling pathway
