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Fabgennix
CDX2 Polyclonal Antibody
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Product Details
CDX2-201AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
N-epitope synthetic peptide taken within amino acid region 1-50 on human CDX2 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caudal type homeo box 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2
Gene Aliases: Cdx-2; CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626, (Mouse) P43241
Entrez Gene ID: (Human) 1045, (Mouse) 12591, (Rat) 66019
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
methyl-CpG binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription corepressor activity
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
blood vessel development
blastocyst development
trophectodermal cell differentiation
placenta development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
pattern specification process
positive regulation of cell proliferation
endosome to lysosome transport
embryonic pattern specification
organ morphogenesis
anterior/posterior axis specification
anterior/posterior pattern specification
regulation of somitogenesis
cell differentiation
somatic stem cell population maintenance
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
stem cell differentiation
intestinal epithelial cell differentiation
labyrinthine layer development
transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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