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          • Primary Antibodies ›
          • Caveolin 1 Antibodies

          Proteintech

          Caveolin-1 Monoclonal Antibody (6C2B2), CoraLite® 594

          查看其他36个Caveolin 1抗体

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          Cite Caveolin-1 Monoclonal Antibody (6C2B2), CoraLite® 594

          Additional Information:

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          • 抗体检测数据 (2)
          Caveolin-1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Group 53 Created with Sketch.
          Caveolin-1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Group 53 Created with Sketch.

          图: 1 / 2

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          Caveolin-1 Antibody (CL594-66067) in IHC (PFA)

          Immunofluorescent analysis of (4% PFA) fixed human skin cancer tissue using CL594-66067 (Caveolin-1 antibody) at dilution of 1:100 {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          Caveolin-1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Caveolin-1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          产品信息

          CL594-66067

          应用
          建议稀释比
          已发表文章

          免疫组织化学(多聚甲醛固定) (IHC (PFA))

          1:50-1:500
          -
          产品规格

          种属反应

          Human, Mouse, Pig, Rat

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          6C2B2

          抗原

          Fusion Protein

          偶联物

          CoraLite® 594 CoraLite® 594 CoraLite® 594
          • Unconjugated
          • CoraLite Plus 488
          • Request custom conjugation

          激发/发射光谱

          593/614 nm

          形式

          Liquid

          浓度

          2 mg/mL

          规格

          200 µg

          纯化类型

          Protein G

          保存液

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          内含物

          0.05% ProClin 300

          保存条件

          -20°C, store in dark

          运输条件

          Wet ice

          靶标信息

          Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          Cite this product

          生物信息学

          蛋白别名: CAV1; caveolae; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-like; cell growth-inhibiting protein 32; GIG32; HGNC:1527; OTTHUMP00000196475; unnamed protein product

          查看更多 收起

          基因别名: BSCL3; Cav; Cav-1; CGL3; LCCNS; MSTP085; PPH3; VIP21

          查看更多 收起

          UniProt ID: (Pig) Q6RVA9, (Human) Q03135, (Mouse) P49817

          查看更多 收起

          Entrez Gene ID: (Pig) 404693, (Human) 857, (Rat) 25404, (Mouse) 12389

          查看更多 收起

          功能
          receptor binding patched binding protein binding oxysterol binding cholesterol binding peptidase activator activity enzyme binding protein kinase binding protein tyrosine kinase inhibitor activity protein binding, bridging small GTPase binding nitric-oxide synthase inhibitor activity identical protein binding ion channel binding macromolecular complex binding protein heterodimerization activity nitric-oxide synthase binding ATPase binding binding, bridging inward rectifier potassium channel inhibitor activity protein sequestering activity SNARE binding kinase binding receptor serine/threonine kinase binding scaffold/adaptor protein
          参与通路
          biological_process negative regulation of transforming growth factor beta receptor signaling pathway T cell costimulation receptor internalization negative regulation of transcription from RNA polymerase II promoter vasculogenesis response to hypoxia negative regulation of endothelial cell proliferation triglyceride metabolic process calcium ion transport cellular calcium ion homeostasis regulation of smooth muscle contraction skeletal muscle tissue development protein localization cellular response to starvation response to bacterium positive regulation of calcium ion transport into cytosol posttranscriptional regulation of gene expression positive regulation of gene expression positive regulation of cholesterol efflux vesicle organization receptor-mediated endocytosis of virus by host cell regulation of fatty acid metabolic process lipid storage cell differentiation regulation of blood coagulation cholesterol transport positive regulation of cell migration negative regulation of BMP signaling pathway negative regulation of epithelial cell differentiation mammary gland development negative regulation of protein ubiquitination positive regulation of protein ubiquitination maintenance of protein location in cell response to progesterone nitric oxide homeostasis insulin receptor internalization angiotensin-activated signaling pathway cholesterol homeostasis positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of MAPK cascade response to estrogen protein localization to plasma membrane raft negative regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction nitric oxide metabolic process negative regulation of JAK-STAT cascade negative regulation of pinocytosis regulation of cytosolic calcium ion concentration response to calcium ion membrane depolarization calcium ion homeostasis mammary gland involution canonical Wnt signaling pathway negative regulation of necroptotic process caveola assembly cellular response to misfolded protein cellular response to peptide hormone stimulus cellular response to hyperoxia caveolin-mediated endocytosis regulation of heart rate by cardiac conduction negative regulation of canonical Wnt signaling pathway apoptotic signaling pathway regulation of membrane repolarization during action potential regulation of cardiac muscle cell action potential involved in regulation of contraction regulation of ventricular cardiac muscle cell action potential positive regulation of cold-induced thermogenesis regulation of ruffle assembly negative regulation of potassium ion transmembrane transport regulation of cell communication by electrical coupling involved in cardiac conduction protein localization to basolateral plasma membrane positive regulation of gap junction assembly positive regulation of ERAD pathway regulation of entry of bacterium into host cell negative regulation of anoikis positive regulation of extrinsic apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway angiogenesis positive regulation of endothelial cell proliferation negative regulation of cytokine-mediated signaling pathway regulation of the force of heart contraction response to ischemia regulation of the force of heart contraction by chemical signal response to nutrient lactation negative regulation of cell proliferation response to xenobiotic stimulus response to mechanical stimulus positive regulation of signal transduction negative regulation of signal transduction response to gamma radiation negative regulation of muscle cell apoptotic process negative regulation of smooth muscle cell migration protein transport organ regeneration positive regulation of microtubule polymerization cholesterol efflux vasoconstriction negative regulation of tyrosine phosphorylation of STAT protein positive regulation of catalytic activity negative regulation of MAP kinase activity negative regulation of neuron differentiation positive regulation of endocytosis microtubule polymerization negative regulation of smooth muscle cell proliferation negative regulation of nitric-oxide synthase activity response to glucocorticoid regulation of peptidase activity negative regulation of ERK1 and ERK2 cascade cellular response to mechanical stimulus cellular response to hypoxia cellular response to transforming growth factor beta stimulus basement membrane organization cellular senescence regulation of potassium ion export across plasma membrane negative regulation of vascular smooth muscle cell proliferation negative regulation of calcium ion import across plasma membrane endocytosis toll-like receptor 4 signaling pathway regulation of toll-like receptor 4 signaling pathway
          It has to be done as per old AB suggested Products section.

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