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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
蛋白别名: CK-8; cytokeratin 8; cytokeratin-8; cytokeratin-A; K8; KERA; keratin 8, type II; type II cytokeratin A (no.8); type-II keratin Kb8; unnamed protein product
基因别名: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; KRT2-8
UniProt ID: (Bovine) P05786, (Human) P05787
Entrez Gene ID: (Rabbit) 100348891, (Bovine) 281269, (Human) 3856, (Pig) 100152077, (Sheep) 101110495