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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: APSCAFPVQFR QPSVSGLSQI TKSLYISNGV AATN
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 71%.
DUSP18 (E.C 3.1.3.16), a novel DSP, is a member of highly conserved protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation and mitogenic signal transduction. DUSP18 is a low molecular weight protein consisting of conserved N-terminal DSP domain but lacks CH2 domain. Studies reveal that DUSP18 is a unique DSP that interacts and dephosphorylates SAPK/JNK. Reports suggest it inhibits SAPK/JNK invivo and might serve an important role in the regulation of SAPK/JNK pathway. Northern Blot analysis detected a ubiquitous expression of DUSP18.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bK963H5.1; low molecular weight dual specificity phosphatase 20; unnamed protein product
基因别名: DSP18; DUSP20; LMWDSP20
UniProt ID: (Human) Q8NEJ0
Entrez Gene ID: (Human) 150290