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          • Primary Antibodies ›
          • SPINK7 Antibodies

          Rockland

          ECRG2 Polyclonal Antibody

          View all (6) SPINK7 antibodies

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          Cite ECRG2 Polyclonal Antibody

          Additional Information:

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          ECRG2 Polyclonal Antibody

          Product Details

          200-901-AY8

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          5 µg/mL
          -

          ELISA (ELISA)

          1:10,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Chicken / IgY

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Anti-ECRG2 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human ECRG2.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.2

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein. Containing one Kazal-like domain, SPINK7 is thought to be a serine protease inhibitor. The gene that encodes SPINK7 maps to human chromosome 5, which contains 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Probable serine protease inhibitor.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: ECRG-2; esophagus cancer-related gene 2 protein; esophagus cancer-related gene-2; esophagus cancer-related protein 2; serine peptidase inhibitor, Kazal type 7 (putative)

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          Gene Aliases: ECG2; ECRG-2; ECRG2; EG408198

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          UniProt ID: (Human) P58062, (Mouse) Q6IE32

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          Entrez Gene ID: (Human) 84651, (Mouse) 408198, (Rat) 408237

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          Function(s)
          serine-type endopeptidase inhibitor activity protein binding
          Process(es)
          inflammatory response negative regulation of proteolysis negative regulation of cytokine production involved in inflammatory response
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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