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Invitrogen
ERAB Polyclonal Antibody
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ERAB Antibody (PA5-85384) in IHC (P)
ERAB Polyclonal Antibody detects ERAB protein at cytoplasm on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. ERAB Polyclonal Antibody (Product # PA5-85384) dilution: 1:250. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-85384
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human ERAB. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (91%), Xenopus laevis (83%), Rhesus Monkey (98%), Bovine (94%).
Positive Control: 293T, HeLa, HepG2, Molt-4, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; AB-binding alcohol dehydrogenase; amyloid-beta peptide binding alcohol dehydrogenase; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; HADH2; HADH2 protein; hydroxysteroid (17-beta) dehydrogenase 10 isoform HSD17B10_1; hydroxysteroid (17-beta) dehydrogenase 10 isoform HSD17B10_2; mitochondrial ribo; mitochondrial ribonuclease P protein 2; mitochondrial RNas; mitochondrial RNase P subunit 2; RP3-339A18.2; short chain L-3-hydroxyacyl-CoA dehydrogenase type 2; short chain type dehydrogenase/reductase XH98G2; type 10 17b-HSD; X-linked alcohol dehydrogenase
基因别名: 17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; HSD10MD; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD; SDR5C1
UniProt ID: (Human) Q99714
Entrez Gene ID: (Human) 3028
tRNA binding
RNA binding
3-hydroxyacyl-CoA dehydrogenase activity
estradiol 17-beta-dehydrogenase activity
protein binding
cholate 7-alpha-dehydrogenase activity
long-chain-3-hydroxyacyl-CoA dehydrogenase activity
17-beta-hydroxysteroid dehydrogenase (NAD+) activity
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
testosterone dehydrogenase (NAD+) activity
androstan-3-alpha,17-beta-diol dehydrogenase activity
chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity
isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
cardiolipin dehydrogenase (NAD+) activity
tRNA 3'-terminal CCA addition
isoleucine catabolic process
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
bile acid biosynthetic process
mitochondrion organization
C21-steroid hormone metabolic process
androgen metabolic process
estrogen metabolic process
tRNA 3'-end processing
protein homotetramerization
brexanolone metabolic process
mitochondrial tRNA methylation
mitochondrial tRNA 5'-end processing
mitochondrial tRNA 3'-end processing
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
