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MA5-15384 targets EhpB6 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.
The MA5-15384 immunogen is purified recombinant fragment of EphB6 (aa601-750) expressed in E. Coli.
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Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EPB6; EphB6v; Epherin B6; Epherin receptor B6; Ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
基因别名: EPHB6; HEP
UniProt ID: (Human) O15197
Entrez Gene ID: (Human) 2051