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Active Motif
H3ac pan-acetyl (K9,K14,K18,K23,K27) Recombinant Rabbit Monoclonal Antibody, AbFlex®
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H3ac pan-acetyl (K9,K14,K18,K23,K27) Antibody (91419ACTMOTIF) in WB
AbFlexHistone H3ac (pan-acetyl) antibody (rAb) tested by Western blot. HeLa nuclear extract (20 μg per lane) was probed with AbFlexHistone H3ac (pan-acetyl) antibody (0.5 μg/mL). Lane 1: HeLa cells no treatment Lane 2: HeLa cells treated with sodium butyrate.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
91419ACTMOTIF
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
This Histone H3 acetyl antibody was raised against an acetylated Histone H3 peptide.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
32mM sodium acetate/140mM HEPES, pH 7.5, with 30% glycerol, 70mM NaCl
内含物
0.035% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Predicted to react with a wide range of species.
AbFlex® antibodies are recombinant antibodies (rAbs) that have been generated using defined DNA sequences to produce highly specific, reproducible antibodies. Each AbFlex antibody contains a 6xHis Tag, a Biotinylation Tag for enzymatic biotin conjugation using the biotin ligase, BirA, and a sortase recognition motif (LPXTG) to attach a variety of labels directly to the antibody including fluorophores, enzymatic substrates (HRP, AP), peptides, drugs as well as solid supports. | AbFlex® Histone H3ac (pan-acetyl) antibody was expressed as full-length IgG with mouse immunoglobulin heavy and light chains (IgG2a isotype) in mammalian 293 cells
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
靶标信息
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acetyl H3; Acetyl Histone 3; Acetyl Histone H3; H3; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member M; H3 histone, family 2; HIST1H3A; HIST1H3F; histone 1, H3a; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; Histone 3; histone cluster 1 H3 family member a; histone cluster 1 H3 family member f; histone cluster 1 H3 family member h; histone cluster 1, H3a; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2 H3 family member a; histone cluster 2 H3 family member c; histone cluster 2, H3a; histone cluster 2, H3c; Histone H3; histone H3/a; histone H3/i; histone H3/k; histone H3/m; histone H3/o; pan-acetyl H3K9, H3K14, H3K18, H3K23, H3K27; unnamed protein product
基因别名: H3; H3.2; H3/A; H3/i; H3/k; H3/M; H3/n; H3/o; H3F1K; H3F2; H3FA; H3FI; H3FK; H3FM; H3FN; HIST1H3A; HIST1H3F; HIST1H3H; HIST2H3A; HIST2H3C
UniProt ID: (Human) P68431, (Human) Q71DI3
Entrez Gene ID: (Human) 8350, (Human) 8357, (Human) 126961, (Human) 333932, (Human) 8968
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
