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Invitrogen
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Immunogen sequence: SKLQSLICGP SFDIASIIPF LEPLSEDTIA GLSVHVLCRT RLKEYEQCID ILLERCPEAV IPYANHELKE ENRTLW
Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 79%.
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BLOC-2 complex member HPS3; cocoa; DKFZp686F0413; FLJ22704; Hermansky-Pudlak syndrome 3 protein
基因别名: BLOC2S1; HPS3; SUTAL
UniProt ID: (Human) Q969F9
Entrez Gene ID: (Human) 84343