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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LACKPFWKPR NLNISQHGSD MQVSFDHAPH NFGFRFFYLH YKLKHEGPFK RKTCKQEQTT ETTSCLLQNV SPGDYIIELV DDTNTTRKVM
Highest antigen sequence indentity to the following orthologs: Rat - 82%, Mouse - 84%.
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hSef; IL-17 receptor D; IL17Rhom; Interleukin-17 receptor D; Interleukin-17 receptor-like protein; Sef homolog
基因别名: IL17RD; IL17RLM; SEF; UNQ6115/PRO20026
Entrez Gene ID: (Human) 54756