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Invitrogen
LIMCH1 Polyclonal Antibody
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产品信息
PA5-34745
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human LIMCH1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.53 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: H1299, HeLaS3, mouse brain.
Predicted reactivity: Mouse (80%), Bovine (86%).
IHC notes, Requires antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: LIM and calponin homology domains-containing protein 1
基因别名: 3732412D22Rik; KIAA1102; LIMCH1; LIMCH1A; LMO7B; mKIAA1102
UniProt ID: (Human) Q9UPQ0, (Mouse) Q3UH68
Entrez Gene ID: (Human) 22998, (Mouse) 77569
