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Invitrogen
LIN7C Polyclonal Antibody
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图: 1 / 4
LIN7C Antibody (51-5600) in ICC/IF
Immunofluorescence analysis of VELI-3 was performed using 70% confluent log phase RSC96 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with LIN7C Rabbit Polyclonal Antibody (Product # 51-5600) at 2µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
51-5600
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Dog,
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from the C-terminus of the rat Velis-3 (MALS-3) protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.1% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Protein assembly at the post synaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PDZ (PSD-95/discs large/zona occludens-1) motifs. The Mammalian LIN-7 (MALS) proteins are a family of small synaptic proteins that are the mammalian homologs of LIN-7, a C. elegans protein essential for vulval development. MALS proteins are also known as Veli (Vertebrate Lin-7) proteins. MALS-3 mRNA is most abundant in kidney, followed by brain, liver, thymus and heart. MALS-3 is undetectable in spleen. In cultured cortical neurons, MALS proteins are clustered together with PSD-95 and NMDA-type glutamate receptors. MALS proteins are suggested to have roles in regulating the recruitment of neurotransmitter receptors to the PSD and in the assembly of proteins involved in synaptic vesicle exocytosis and synaptic junctions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ11215; lin 7 homolog c; lin-7 homolog C; lin-7 homolog C, crumbs cell polarity complex component; LIN-7 protein 3; mammalian LIN-7 3; mammalian lin-seven protein 3; similar to Caenorhabditis elegans LIN-7; unnamed protein product; veli-3; veli-3 protein; vertebrate homolog of C. elegans Lin-7 type 3; vertebrate lin-7 homolog 3; vertebrate LIN7 homolog 3
基因别名: 9130007B12Rik; D2Ertd520e; LIN-7-C; LIN-7C; MALS-3; MALS3; VELI3
UniProt ID: (Human) Q9NUP9, (Rat) Q792I0, (Mouse) O88952
Entrez Gene ID: (Human) 55327, (Dog) 485424, (Rat) 60442, (Mouse) 22343
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