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Invitrogen
LPHN2 Polyclonal Antibody
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产品信息
PA5-65359
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human LPHN2
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.3 mg/mL
规格
30 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: PVKPVIGGSSS EDDAIVADAS SLMHSDNPGL ELHHKELEAP LIPQRTHSLL YQPQKKVKSE GTDSYVSQLT AEAEDHLQS
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 91%.
靶标信息
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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