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Invitrogen
LRFN5 Polyclonal Antibody
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产品信息
PA5-51529
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.10 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PEGKLISNAT RSLVYDNGTL DILITTVKDT GAFTCIASNP AGEATQIVDL HIIKLPHLLN STNHIHEPDP GSSDISTSTK SGSNTSSSNG DTKLSQDKIV VAEATSSTAL LKFNFQRNIP GIRMFQIQYN GTYDDTLVYR MIPP
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 96%.
靶标信息
LRFN5 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fibronectin type III, immunoglobulin and leucine rich repeat domains 8; Leucine-rich repeat and fibronectin type-III domain-containing protein 5
基因别名: C14orf146; FIGLER8; LRFN5; SALM5
UniProt ID: (Human) Q96NI6
Entrez Gene ID: (Human) 145581
