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Invitrogen
LexA Polyclonal Antibody
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产品信息
PA1-4966
应用
建议稀释比
已发表文章
产品规格
种属反应
Bacteria,
Yeast
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Full size LexA recombinant protein.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
whole serum
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-4966 detects LexA protein in E.coli and yeast samples.
PA1-4966 has been successfully used in Western blot, immunoprecipitation and immunohistochemical procedures. It is specific for the ~23 kDa LexA protein.
PA1-4966 immunogen is a highly purified recombinant full size LexA protein.
Store at -20°C.
靶标信息
E. coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence. LexA‘s self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells. It is cleaved into two fragments and loses its function as a repressor. As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
