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Proteintech
MVP/LRP Polyclonal Antibody, CoraLite® Plus 488
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产品信息
CL488-16478
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MVP/LRP fusion protein Ag9593
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: NWHFEVNDR KDPQETAKLF SVPDFVGDAC KAIASRVRGA VASVTFDDFH KNSARIIRTA VFGFETSEAK GPDGMALPRP RDQAVFPQNG LVVSSVDVQS VEPVDQRTRD ALQRSVQLAI EITTNSQEAA AKHEAQRLEQ EARGRLERQK ILDQSEAEKA RKELLELEAL SMAVESTGTA KAEAESRAEA ARIEGEGSVL QAKLKAQALA IETEAELQRV QKVRELELVY ARAQLELEVS KAQQLAEVEV KKFKQMTEAI GPSTIRDLAV AGPEMQVKLL QSLGLKSTLI TDGSTPINLF NTAFGLLGMG PEGQPLGRRV ASGPSPGEGI SPQSAQAPQA PGDNHVVPVL R
靶标信息
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Lung resistance-related protein; Major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
基因别名: 2310009M24Rik; LRP; MVP; VAULT1
UniProt ID: (Human) Q14764, (Rat) Q62667, (Mouse) Q9EQK5
Entrez Gene ID: (Human) 9961, (Rat) 64681, (Mouse) 78388
