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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PPINKLALFP DKSAWCEAKN ITQIVGHSGC EAKSIQNRAC LGQCFSYSVP NTFPQSTESL VHCDSCMPAQ SMWEIVTLEC PGHEEVPRVD KLVEKILHCS CQACGKEPSH EGLSVYVQGE DGPGSQPGTH PHPHPHPHPG GQTPEPE
Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 95%.
This gene product is the founding member of the evolutionarily conserved CAN family of proteins, which contain a domain resembling the CTCK motif found in a number of signaling molecules. These proteins are secreted, and act as BMP antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DAN domain family member 1; differential screening-selected gene aberrant in neuroblastoma; neuroblastoma 1, DAN family BMP antagonist; neuroblastoma candidate region, suppression of tumorigenicity 1; neuroblastoma, suppression of tumorigenicity 1; unnamed protein product
基因别名: D1S1733E; DAN; DAND1; NB; NO3
UniProt ID: (Human) P41271
Entrez Gene ID: (Human) 4681