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Invitrogen
NELL1 Polyclonal Antibody
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NELL1 Antibody (PA5-47900) in IHC (F)
Immunohistochemical analysis of NELL1 in immersion fixed frozen sections of mouse embryo (13 d.p.c.). Samples were incubated in NELL1 polyclonal antibody (Product # PA5-47900) using a dilution of 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to neurons in the spinal cor... View More
产品信息
PA5-47900
产品规格
种属反应
Mouse
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHO-derived recombinant mouse NELL1 Arg17-Asn810
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, approximately 25% cross-reactivity with recombinant human NELL1 is observed and approximately 10% cross-reactivity with recombinant mouse NELL2 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
靶标信息
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NEL-like protein 1; Protein kinase C-binding protein NELL1
基因别名: B230343H07Rik; l7R6; Nell1
UniProt ID: (Mouse) Q2VWQ2
Entrez Gene ID: (Mouse) 338352
regulation of gene expression
cell differentiation
positive regulation of bone mineralization
negative regulation of osteoblast proliferation
positive regulation of apoptotic process
regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
protein homotrimerization
negative regulation of cyclin catabolic process
