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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: IKFLPVDARR QPGPPPGPGS HTGW
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 67%.
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAP-binding protein complex-interacting protein 2; Protein orai-2; Transmembrane protein 142B
基因别名: C7orf19; CBCIP2; ORAI2; PP1729; TMEM142B
Entrez Gene ID: (Human) 80228