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Invitrogen
PIAS2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-145166
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MRPKKEAMKV SSQPCTKIES SSVLSKPCSV TVASEASKKK VDVI
Antigen sequence identity: Mouse 89%; Rat 89%
靶标信息
This gene encodes a protein involved in the regulation of transcription factors involved in MAP kinase signaling. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. Two alternatively spliced transcripts encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: androgen receptor-interacting protein 3; DAB2-interacting protein; E3 SUMO-protein transferase PIAS2; MGC102682; msx-interacting zinc finger protein; protein inhibitor of activated STAT X; unnamed protein product; zinc finger, MIZ-type containing 4
基因别名: ARIP3; DIP; MIZ1; PIASX; SIZ2; ZMIZ4
UniProt ID: (Human) O75928
Entrez Gene ID: (Human) 9063
DNA binding
transcription cofactor activity
transcription corepressor activity
protein binding
zinc ion binding
SUMO transferase activity
ubiquitin protein ligase binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
SUMO ligase activity
transcription regulator inhibitor activity
regulation of transcription from RNA polymerase II promoter
transforming growth factor beta receptor signaling pathway
protein sumoylation
endoplasmic reticulum unfolded protein response
negative regulation of transcription, DNA-templated
negative regulation of JAK-STAT cascade
SMAD protein signal transduction
negative regulation of androgen receptor signaling pathway
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