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Proteintech
PLA2G1B Monoclonal Antibody (1F2C10)
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产品信息
66397-1-IG
产品规格
种属反应
Human,
Pig
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
1F2C10
抗原
PLA2G1B Fusion Protein Ag8812 (1-70 aa encoded by BC005386)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MKLLVLAVL LTVAAADSGI SPRAVWQFRK MIKCVIPGSD PFLEYNNYGC YCGLGGSGTP VDELDKQKQR V (1-70 aa encoded by BC005386)
靶标信息
Phospholipase A2 catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Group IB phospholipase A2; group IB secretory phospholipase A(2); MGC119834; MGC119835; Phosphatidylcholine 2-acylhydrolase 1B; Phospholipase A2; phospholipase A2, group IB (pancreas); Phospholipase A2, major isoenzyme; unnamed protein product
基因别名: PLA2; PLA2A; PLA2G1B; PPLA2; sPLA(2)-IB
UniProt ID: (Pig) P00592, (Human) P04054
Entrez Gene ID: (Pig) 445525, (Human) 5319
activation of MAPK activity
neutrophil mediated immunity
fatty acid biosynthetic process
positive regulation of cell proliferation
positive regulation of calcium ion transport into cytosol
lipid catabolic process
leukotriene biosynthetic process
neutrophil chemotaxis
interleukin-1 production
interleukin-8 production
cellular response to insulin stimulus
intracellular signal transduction
positive regulation of transcription from RNA polymerase II promoter
regulation of glucose import
phosphatidylcholine metabolic process
phosphatidylglycerol metabolic process
positive regulation of fibroblast proliferation
arachidonic acid secretion
positive regulation of immune response
positive regulation of NF-kappaB transcription factor activity
positive regulation of glomerular visceral epithelial cell apoptotic process
innate immune response in mucosa
phosphatidic acid biosynthetic process
actin filament organization
signal transduction
glucose transport
antibacterial humoral response
activation of phospholipase A2 activity
phosphatidylglycerol acyl-chain remodeling
phosphatidylinositol acyl-chain remodeling
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
multicellular organism lipid catabolic process
positive regulation of DNA replication
positive regulation of protein secretion
defense response to Gram-positive bacterium
