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Invitrogen
PMS2 Polyclonal Antibody
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PMS2 Antibody (PA5-79837) in WB
Western blot analysis of PMS2 in Lane 1: human HeLa whole cell lysate using 50 µg (reducing conditions) per well. Electrophoresis was performed on 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours and protein was transferred to a nitrocellulose membrane at 150mA for 50-90 minutes. Sample was blocked with 5% Non-fat Milk/TBS for 1.5 hours at room temperature, incubated with PMS2 polyclonal antibody (Product # PA5-79837) at a dilution of 0.5 µg/mL (overnight at 4°C), followed by goat anti-rabbit IgG-HRP secondary a... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79837
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human PMS2 recombinant protein (Position: E656-L767).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell.
靶标信息
PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA mismatch repair protein PMS2; H_DJ0042M02.9; PMS1 homolog 2, mismatch repair protein; PMS1 protein homolog 2; PMS2 postmeiotic segregation increased 2; postmeiotic segregation increased 2; similar to S. cerevisiae PMS1 Swiss-Prot Accession Number P14242, S. cerevisiae MLH1 GenBank Accession Number U07187, E. coli MUTL Swiss-Prot Accession Number P23367, Salmonella typhimurium MUTL Swiss-Prot Accession Number P14161, Streptococcus pneumoniae ; unnamed protein product
基因别名: HNPCC4; LYNCH4; MLH4; MMRCS4; PMS-2; PMSL2
UniProt ID: (Human) P54278, (Mouse) P54279
Entrez Gene ID: (Human) 5395, (Rat) 288479, (Mouse) 18861
meiotic mismatch repair
DNA repair
mismatch repair
cellular response to DNA damage stimulus
response to xenobiotic stimulus
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
positive regulation of isotype switching to IgA isotypes
positive regulation of isotype switching to IgG isotypes
meiotic cell cycle
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