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Invitrogen
PPARGC1A Polyclonal Antibody
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PPARGC1A Antibody (PA5-38022) in ICC/IF
Immunofluorescent analysis of 4% paraformaldehyde-fixed MCF7 cells labeling PPARGC1A with PGC1 alpha Polyclonal Antibody (Product # PA5-38022) at 20 µg/mL, followed by goat anti-rabbit IgG secondary antibody at 1:500 dilution (green) and DAPI staining (blue).
产品信息
PA5-38022
应用
建议稀释比
已发表文章
产品规格
已发表种属
C. elegans,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
17 amino acid peptide near the amino terminus of human PPARGC1A
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Wet ice
RRID
产品详细信息
A recommended positive control is human heart tissue lysate.
At least three isoforms of PPARGC1A are known to exist; this antibody will detect all three isoforms.
靶标信息
PGC1 alpha is a transcriptional coactivator that regulates the genes involved in energy metabolism. It interacts with PPARgamma, which permits it's interaction with multiple transcription factors. PGC-1 Alpha can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. It may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
